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The specificity of the antibody responses of human volunteers to certain respiratory viruses

Published online by Cambridge University Press:  15 May 2009

F. E Buckland ,
Jennifer E Doggett  and
D. A. J Tyrrell
F. E Buckland
Affiliation:
The Medical Research Council, Common Cold Research Unit, Salisbury, England
Jennifer E Doggett
Affiliation:
The Medical Research Council, Common Cold Research Unit, Salisbury, England
D. A. J Tyrrell
Affiliation:
The Medical Research Council, Common Cold Research Unit, Salisbury, England
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Experiments reported here were performed on the sera of thirty-three volunteers who were infected or inoculated intranasally or intramuscularly in groups of five to nine with one of two enteroviruses, namely, echovirus 11 and coxsackievirus A21 or with one of three rhinoviruses, namely, M viruses P.K. and ECHO 28, and H virus D.C. Antibody responses occurred against the virus administered, and rarely against the other viruses used. It was concluded that although these viruses are related biologically the antibody responses in the volunteers were largely specific.

Type
Research Article
Information
Journal of Hygiene , Volume 62 , Issue 1 , March 1964 , pp. 115 - 119
Copyright
Copyright © Cambridge University Press 1964

References

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