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Specificity of early protective responses induced by pseudomonas vaccines

Published online by Cambridge University Press:  15 May 2009

R. J. Jones
R. J. Jones
Affiliation:
MRC Industrial Injuries and Burns Unit, Birmingham Accident Hospital, Bath Row, Birmingham B15 1NA
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Summary

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A single inoculation of pseudomonas vaccine protected mice against a 1 LD 100 challenge by nine different serotypes of Pseudomonas aeruginosa, 4 days after vaccination. Three inoculations of the same vaccine, given on consecutive days, protected mice for a longer time, against challenge by a wide range of Ps. aeruginosa serotypes, than the single inoculation of vaccine. The amount of vaccine inoculated only marginally influenced the non-specific response. F1 vaccines from eight serotypes of Ps. aeruginosa each induced protection against a different range of serotypes.

Type
Research Article
Information
Journal of Hygiene , Volume 70 , Issue 2 , June 1972 , pp. 343 - 351
Copyright
Copyright © Cambridge University Press 1972

References

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