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Some properties of calciferol as a rodenticide*

Published online by Cambridge University Press:  15 May 2009

J. H. Greaves ,
R. Redfern  and
R. E. King
J. H. Greaves
Affiliation:
Pest Infestation Control Laboratory, Ministry of Agriculture, Fisheries and Food, Hook Rise South, Tolworth, Surbiton, Surrey
R. Redfern
Affiliation:
Pest Infestation Control Laboratory, Ministry of Agriculture, Fisheries and Food, Hook Rise South, Tolworth, Surbiton, Surrey
R. E. King
Affiliation:
Pest Infestation Control Laboratory, Ministry of Agriculture, Fisheries and Food, Hook Rise South, Tolworth, Surbiton, Surrey
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The potentiality of calciferol (alone and combined with warfarin) for the control of commensal rats and mice has been examined in the laboratory. Nearly all animals fed on 0·1% calciferol for 2 days died. Though illness usually reduced food intake after the first 24 hr. there was no sign of aversion to the poison at 0·1 % – which is considered to be the lowest concentration suitable for use against Rattus norvegicus, R. rattus and Mus musculus in the field. There was some indication that resistance to warfarin in R. norvegicus may be correlated with susceptibility to calciferol. Toxicity tests with calciferol combined with warfarin indicated an additive effect between the compounds. No evidence for synergism was found however, although elsewhere there is some evidence for this.

Type
Research Article
Information
Journal of Hygiene , Volume 73 , Issue 3 , December 1974 , pp. 341 - 351
Copyright
Copyright © Cambridge University Press 1974

References

REFERENCES

Elliott, M. C., Isaacs, B. & Ivy, A. C. (1940). Production of prothrombin deficiency and response to vitamins A, D and K. Proceedings of the Society for Experimental Biology & Medicine 43, 240–5.Google Scholar
Finney, D. J. (1971). Probit Analysis (3rd edition). CambridgeUniversity Press.Google Scholar
Greaves, J. H. (1971). Resistance to anticoagulants in rodents. Pesticide Science 2, 276–9.Google Scholar
Greaves, J. H. & Ayres, P. (1973). Warfarin resistance and vitamin K requirement in the rat. Laboratory Animals 7, 141–8.Google Scholar
Hass, G. M., Trueheart, R. E. & Hemmens, A. (1960). Experimental arteriosclerosis due to hypervitaminosis D. American Journal of Pathology 37, 521–49.Google ScholarPubMed