The idea of having the means of applying the Anti-rabic treatment of Pasteur in Shanghai, China, had its origin in the marked incidence of rabies among the numerous dogs of the Shanghai district and the consequent large mortality from this disease. The local condition was the more marked because of the short incubation period observed in Shanghai both in the human subject and in the rabbit inoculated from the rabid dog, being seldom much over a month in man and rarely over two weeks in rabbits inoculated subdurally.