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Serum antibody to poliovirus in patients in a mental deficiency hospital, with particular reference to Down's syndrome

Published online by Cambridge University Press:  15 May 2009

Eric McKay ,
Gordon Hems ,
Alexander Massie ,
Margaret A. J. Moffat  and
Kathleen McL. Phillips
Eric McKay
Affiliation:
Raeden Centre, Midstocket Road, Aberdeen
Gordon Hems
Affiliation:
Departments of Community Medicine and Statistics, University of Aberdeen
Alexander Massie
Affiliation:
Diagnostic Virus Laboratory, Department of Bacteriology, University of Aberdeen
Margaret A. J. Moffat
Affiliation:
Diagnostic Virus Laboratory, Department of Bacteriology, University of Aberdeen
Kathleen McL. Phillips
Affiliation:
Department of Child Health, University of Aberdeen
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Summary

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Neutralization tests for poliovirus antibodies were carried out on 74 patients in an adult mental deficiency hospital: 37 patients with Down's syndrome and 37 non- Down's mental defectives. The distribution of antibody titres to poliovirus types 1, 2 and 3 did not differ significantly between the two groups. Most patients had antibody to at least one poliovirus typebut less than a third had antibodies at a titre of 1/8 or greater to all three types. The low level of poliovirus immunity in this population may be of epidemiological importance.

Type
Research Article
Information
Journal of Hygiene , Volume 81 , Issue 1 , August 1978 , pp. 25 - 30
Copyright
Copyright © Cambridge University Press 1978

References

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