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Sero/subtyping of Neisseria meningitidis isolated from patients in Spain

Published online by Cambridge University Press:  15 May 2009

J. A. Vazquez ,
C. Marcos  and
S. Berron
J. A. Vazquez
Affiliation:
Servicio de Bacteriología, Centra Nacional de Microbiologí, Instituto de Salud Carlos III, 28220 Majadahonda (Madrid), Spain
C. Marcos
Affiliation:
Servicio de Bacteriología, Centra Nacional de Microbiologí, Instituto de Salud Carlos III, 28220 Majadahonda (Madrid), Spain
S. Berron
Affiliation:
Servicio de Bacteriología, Centra Nacional de Microbiologí, Instituto de Salud Carlos III, 28220 Majadahonda (Madrid), Spain
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Summary

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To know the types of meningococcal strains in Spain, we serotyped and subtyped 743 Neisseria meningitidis isolates recovered between 1990 and 1992 from patients. A great number of serogroup B, serogroup C and non-groupable meningoccoci reacted with the serotyping reagents while many serogroup C and non-groupable isolates did not react with the serosubtyping reagents (78·2% and 54·8 % respectively); only 8·9 % of serogroup B meningococci were non-subtypeable (NST). Distribution of serotypes was similar in serogroup C and in non-groupable strains. Isolates showed great variability in antigenic phenotypes (71 in serogroup B, 20 in serogroup C and 25 in non-groupable meningococci). The most frequent antigenic combinations were 4:P1. 15 (39·8%) in serogroup B, 2b:NST (55·8%) in serogroup C and 2b:NST (35·6%) in non-groupable meningococci.

Type
Research Article
Information
Epidemiology & Infection , Volume 113 , Issue 2 , October 1994 , pp. 267 - 274
Copyright
Copyright © Cambridge University Press 1994

References

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