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Seroepidemiology of Helicobacter pylori infection in vegans and meat-eaters

Published online by Cambridge University Press:  15 May 2009

M. J. Webberley
Affiliation:
Dudley Road Hospital, Birmingham
J. M. Webberley*
Affiliation:
Sandwell District Hospital, West Bromwich
D. G. Newell
Affiliation:
PHLS, Centre for Applied Microbiology and Research, Porton Down, Salisbury
P. Lowe
Affiliation:
Dudley Road Hospital, Birmingham
V. Melikian
Affiliation:
Dudley Road Hospital, Birmingham
*
*Author for correspondence and reprint requests: Dr J. M. Webberley, Department of Microbiology, Worcester Royal Infirmary, Castle St, Worcester WR1 3AS, UK.
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Summary

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An enzyme-linked immunosorbent assay has been used to diagnose serologically the prevalence of Helicobacter pylori infection in Asian life-long vegans. There was no difference in the seropositivity between these individuals and a group of age-and sex-matched Asian meat-eaters, indicating the meat consumption is not a risk factor for H. pylori infection. However, both Asian groups had a higher prevalence of infection than age- and sex-matched Caucasian meat-eaters. Additionally, the Asian individuals had a wider range of specific IgG antibody concentrations than the Caucasians. This did not appear to be due to antigenic cross-reactivity between H. pylori and Campylobacter jejuni. The significance of these observations to the establishment of cut-off levels for the serodiagnosis of certain ethnic groups is discussed.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1992

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