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Seroepidemiology of H1N1 influenza: the infection and re-infection rate in winter 1978–79

Published online by Cambridge University Press:  25 March 2010

R. Pyhälä  and
K. Aho
R. Pyhälä
Affiliation:
Central Public Health Laboratory (CPHL), Helsinki, Finland
K. Aho
Affiliation:
Central Public Health Laboratory (CPHL), Helsinki, Finland
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Summary

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It was observed that small children and pregnant women were affected to only a small extent by the H1N1 influenza outbreak of winter 1978–79. This supports earlier findings from the epidemic season of 1977–78 and demonstrates that the evolutionary changes in the epidemic virus were not reflected in any appreciable way in this curious phenomenon. The frequency of elderly subjects possessing antibodies against the epidemic H1N1 virus was low, and virtually equal in the pre-epidemic and post-epidemic sampling. This low attack rate contrasts with observations on young military servicemen, in whom the re-infection rate was high, thus indicating that the infection with the winter 1977–78 virus had conferred only modest protection against the closely related virus which caused the winter 1978–79 outbreak.

Type
Research Article
Information
Journal of Hygiene , Volume 86 , Issue 1 , February 1981 , pp. 27 - 33
Copyright
Copyright © Cambridge University Press 1981

References

REFERENCES

Frank, A. L., Taber, L. H., Glezen, W. P., Paredes, A. & Couch, R. B. (1979). Reinfection with influenza A (H3N2) virus in young children and their families. Journal of Infectious Diseases 140, 829–36.CrossRefGoogle ScholarPubMed
Haaheim, L. R. (1979). Surveillance of the antibody status to current influenza strains in the Norwegian population. 1. Method of serum sampling and evaluation o0f the A“USSR“77 (H1N1) impact in various age groups in 1978. NIPH Annals 2, 45–54.Google Scholar
Nakajima, K., Nakajima, S., Nerome, K., Takeuchi, Y., Sugiura, A. & Oya, A. (1979). Genetic relatedness of some 1978–79 influenza H1N1 strains to 1953 H1N1 strains. Virology 99, 423–6.Google Scholar
Pereira, M. S. (1979). Global surveillance of influenza. British Medical Bulletin 35, 9–14.Google Scholar
Potter, C. W. & Oxford, J. 8. (1979). Determinants of immunity to influenza infection in man. British Medical Bulletin 35, 69–75.Google Scholar
Pyhälä, R. (1979). H1N1 influenza and old people. FEMS Microbiology Letters 6, 175–6.CrossRefGoogle Scholar
Pyhälä, R., Aho, K. & Visakorpi, R. (1970). Seroepidemiology of H1N1 influenza: striking differences in the attack rate among young people. Acta Pathologica et Microbiologica Scandinavica 87 B, 161–4.Google Scholar
Robinson, R. Q. & Dowdle, W. R. (1969). Influenza viruses. In Diagnostic Procedures for Viral and Rickettsial Infections (ed. Lennette, E. H. and Schmidt, N. J.), pp. 426–7. New York: American Public Health Association.Google Scholar
World Health Organization (1979 a). Influenza in the World. October 1977–September 1978. Weekly Epidemic Record 54, 25–8.Google Scholar
World Health Organization (1979 b). Influenza surveillance. Weekly Epidemic Record 54, 126.Google Scholar
Young, J. F. & Palese, P. (1979). Evolution of human influenza A viruses in nature: recombination contributes to genetic variation of H1N1 strains. Proceedings of the National Academy of Science U.S.A. 76, 6547–51.CrossRefGoogle ScholarPubMed