Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-22T16:54:17.046Z Has data issue: false hasContentIssue false
  • English
  • Français

Second Report on the Identification of the Meningococcus in the Naso-Pharynx, with special reference to Serological Reactions1

Published online by Cambridge University Press:  15 May 2009

Fred Griffith
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The serological characters of 66 strains of meningococci obtained from the cerebro-spinal fluid in cases of meningitis have been studied. Serological tests of a similar nature have been applied to 86 strains of Gram-negative cocci, culturally identical with meningococci, obtained from the naso-pharynx of non-contacts. The two series have been compared in respect of agglutinability, agglutinogenic capacity, and absorptive capacity with the following results:

The majority of the spinal strains can be divided into two main groups by simple agglutination tests with selected spinal sera: about 27 can be assigned to Group I and 34 to Group II, the remaining five being relatively inagglutinable or equally agglutinated by sera of both groups.

Type
Research Article
Information
Journal of Hygiene , Volume 17 , Issue 2-3 , July 1918 , pp. 124 - 190
Copyright
Copyright © Cambridge University Press 1918

References

page 125 note 1 Reprinted in Journ. of Hygiene, xv. 446.Google Scholar

page 135 note 1 Later tests, however, showed that several were agglutinated by other spinal sera of Group II, M 18 and M 24. (See Table II.)

page 165 note 1 Journ. of Hygiene, xv. p. 432.Google Scholar

page 165 note 2 Brit. Med. Journ., 12 18th, 1915.Google Scholar

page 165 note 3 Gordon and Murray (1915), Journ. Royal Army Med. Corps, xxv.Google Scholar

page 172 note 1 Medical Research Committee. Report upon Bacteriological Studies of Cerebro-spinal Fever during the Epidemic of 1915.

page 173 note 1 Joum. of Hygiene, ix.Google Scholar

page 173 note 2 Bacteriological Studies, etc. Medical Research Committee, Special Report Series, No. 3.

page 174 note 1 Identification of the Meningococcus. Journ. Royal Army Med. Corps, 10, 1915.Google Scholar

page 174 note 2 Journ. Royal Army Med. Corps, 01, 1916.Google Scholar

page 175 note 1 Proc. Royal Soc. Medicine, vii. (Pathological Section).Google Scholar

page 177 note 1 Journ. of Hygiene, xv. 405.Google Scholar

page 177 note 2 Changes in the Agglutinability, Fermentation Reactions and Absorptive Capacities of the Meningococcus during the Acute Attack. Journ. Royal Army Med. Corps, 10, 1916.Google Scholar

page 180 note 1 Brit. Med. Jaurn., ii. 881 and 885.Google Scholar

page 180 note 2 Gordon and Murray. Journ. Royal Army Med. Corps, xxv. 411.Google Scholar

page 181 note 1 Special Report Series, No. 3, pp. 16–18.

page 181 note 2 Journ. of Hygiene, ix.Google Scholar

page 181 note 3 Report to the Local Government Board, 1907.

page 182 note 1 Centralbl. f. Bakteriol. Orig. LXXIX. 71.Google Scholar

page 184 note 1 Brit. Med. Journ., 1915, ii.Google Scholar

page 189 note 1 In respect of the termination of the disease in these cases Dr Whitley kindly gave me the following information:

Of the 7 infected with Group I strains, 5 died and 1 recovered; in 1 the disease has become chronic and the result is yet in doubt.

Of the 3 infected with Group II strains 1 died and 2 recovered; strains with identical serological characters produced in one case a mild disease and in another a fulminating type.