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Risk factors for hospitalization due to respiratory syncytial virus infection among infants in the Basque Country, Spain

Published online by Cambridge University Press:  21 November 2005

G. CILLA ,
A. SARASUA ,
M. MONTES ,
N. AROSTEGUI ,
D. VICENTE ,
E. PÉREZ-YARZA  and
E. PÉREZ-TRALLERO
G. CILLA
Affiliation:
Servicio de Microbiología, Hospital Donostia, San Sebastián, Spain
A. SARASUA
Affiliation:
Servicio Pediatría, Hospital Donostia, San Sebastián, Spain
M. MONTES
Affiliation:
Servicio de Microbiología, Hospital Donostia, San Sebastián, Spain
N. AROSTEGUI
Affiliation:
Servicio Pediatría, Hospital Donostia, San Sebastián, Spain
D. VICENTE
Affiliation:
Servicio de Microbiología, Hospital Donostia, San Sebastián, Spain
E. PÉREZ-YARZA
Affiliation:
Servicio Pediatría, Hospital Donostia, San Sebastián, Spain
E. PÉREZ-TRALLERO
Affiliation:
Servicio de Microbiología, Hospital Donostia, San Sebastián, Spain Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad del País Vasco, San Sebastián, Spain
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Abstract

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This study analysed the role of several risk factors for hospitalization due to community-acquired, respiratory syncytial virus (RSV) infection. The risk factors detected in infants hospitalized for RSV infection in the first 24 months of life were compared with those in the general infant population in our region. There were 361 episodes of hospitalization in 357 infants. Eighty per cent of the infants did not present underlying conditions for severe RSV infection and only 10 (3%) were candidates for palivizumab prophylaxis. In multivariate analysis, birthweight of <2500 g was independently associated with hospitalization for RSV infection and was the most commonly detected medical risk factor. Other risk factors were maternal age at delivery <25 years, birth in the second half of the year, prematurity, suburban residence and congenital heart disease. In conclusion, together with well-known risk factors, we found that low birthweight was an independent factor for severe RSV infection.

Type
Research Article
Information
Epidemiology & Infection , Volume 134 , Issue 3 , June 2006 , pp. 506 - 513
Copyright
2005 Cambridge University Press