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Replacement coliform flora in carriers of intestinal pathogens

Published online by Cambridge University Press:  15 May 2009

G. T Stewart ,
R. J Holt ,
H. M. T Coles  and
K. M Bhat
G. T Stewart
Affiliation:
Queen Mary's Hospitalfor Children, Carshalton
R. J Holt
Affiliation:
Queen Mary's Hospitalfor Children, Carshalton
H. M. T Coles
Affiliation:
Queen Mary's Hospitalfor Children, Carshalton
K. M Bhat
Affiliation:
Queen Mary's Hospitalfor Children, Carshalton
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Eight carriers of intestinal pathogens (5 Salm. typhi-murium, 2 Sh. sonnei, 1 E. coli 026) were given their own coliforms, rendered drug-resistant in vitro to neomycin or paromomycin, together with one of these drugs. In seven cases, the drug-resistant coliform flora established itself, while the natural coliform flora and the pathogen were suppressed. In four cases only (2 Sh. sonnei, 2 Salm. typhi-murium) the pathogen was eliminated in the course of this procedure.

Type
Research Article
Information
Journal of Hygiene , Volume 62 , Issue 1 , March 1964 , pp. 39 - 44
Copyright
Copyright © Cambridge University Press 1964

References

REFERENCES

Coles, H. M. T. & Stewart, G. T. (1961). Paromomycin. Practitioner, 186, 379.Google Scholar
Stewart, G. T., Coles, H. M. T., Nixon, H. H. & Holt, R. J. (1961). ‘Penbritin’: an oral penicillin with broad spectrum activity. Brit. med. J. ii, 200.Google Scholar
Szybalski, W. (1952). Gradient plates for the study of microbial resistance to antibiotics. Bact. Proc. (1952). p. 36.Google Scholar