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The reduction of the carcinogenic and dermatitic activity of shale oil recovered from the peritoneal cavities of injected mice

Published online by Cambridge University Press:  15 May 2009

J. M. Twort
Affiliation:
The Laboratories of the Manchester Committee on Cancer
R. Lyth
Affiliation:
The Laboratories of the Manchester Committee on Cancer
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1. A carcinogenic Persian spindle grade oil recovered after 4 days from the peritoneal cavities of injected rabbits showed indications of reduced carcinogenic activity for the skins of mice.

2. The activity of a carcinogenic shale oil recovered after 7 days from the peritoneal cavities of injected mice was found to be considerably reduced. The reduction in refractive index and potency of the recovered shale oil showed an obvious parallel to that resulting from certain chemical treatments, namely, treatment of the oil with a certain quantity of sulphuric acid or extraction with alcohol.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1940

References

REFERENCES

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