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Reactions and antibody response to live influenza vaccine prepared from the Iksha (A2) strain. (A report to the Medical Research Council by their Committee on Influenza and other Respiratory Virus Vaccines*)

Published online by Cambridge University Press:  15 May 2009

A. S. Beare ,
D. A. J. Tyreell ,
J. C. McDonald ,
T. M. Pollock ,
C. E. D. Taylor ,
C. H. L. Howells  and
L. E. Tyler
A. S. Beare
Affiliation:
Common Cold Research Unit, Salisbury
D. A. J. Tyreell
Affiliation:
Common Cold Research Unit, Salisbury
J. C. McDonald
Affiliation:
Central Public Health Laboratory, Colindale Avenue, London, N.W. 9
T. M. Pollock
Affiliation:
Central Public Health Laboratory, Colindale Avenue, London, N.W. 9
C. E. D. Taylor
Affiliation:
Central Public Health Laboratory, Colindale Avenue, London, N.W. 9
C. H. L. Howells
Affiliation:
New Cross Hospital, Wolverhampton
L. E. Tyler
Affiliation:
Wednesfield, Wolverhampton
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Two field trials of A 2 live influenza vaccine (Iksha) are described; the clinical reactions and antibody response in three earlier trials are compared.

The antibody response in the last two trials was unsatisfactory and was inferior to that observed in the earlier investigations. This reduction in response was probably due to an alteration in the virus during further passage.

Type
Research Article
Information
Journal of Hygiene , Volume 65 , Issue 2 , June 1967 , pp. 245 - 254
Copyright
Copyright © Cambridge University Press 1967

References

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