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Priorities in global measles control: report of an outbreak in N'Djamena, Chad

Published online by Cambridge University Press:  15 May 2009

A. Ndikuyeze ,
A. Cook ,
F. T. Cutts  and
S. Bennett
A. Ndikuyeze
Affiliation:
World Health Organization, Chad
A. Cook
Affiliation:
London School of Hygiene and Tropical Medicine. Keppel Street, London WC1E 7HT, UK
F. T. Cutts*
Affiliation:
London School of Hygiene and Tropical Medicine. Keppel Street, London WC1E 7HT, UK
S. Bennett
Affiliation:
London School of Hygiene and Tropical Medicine. Keppel Street, London WC1E 7HT, UK
*
* For correspondence and reprints.
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In N'Djamena, capital of Chad, measles vaccination coverage of 12–23-month-old children fell from 61% in 1990 to 15% in 1993. A community survey of measles after an outbreak in 1993 showed that among children < 5 years of age, the mean monthly attack rate was 37 per 1000 (95% CI, 32–43) and the mean case fatality rate was 7·4%. Measles incidence was highest (77/1000/month) in children aged 9–11 months and fell among children > 3 years of age. Incidence rates were high (56/1000/month) among 6–8-month-old children, but only 3 deaths occurred in this age group. Measles vaccine efficacy, estimated by comparing attack rates in unvaccinated and vaccinated children, was 71 % (95% CI, 59–80%). Extrapolation of the results to the city population indicated that an estimated 19000 cases and > 1000 measles-associated deaths occurred in 1993. This preventable morbidity and mortality, in a city where coverage was formerly among the highest in Africa, shows the need for sustained global commitment to preventive health care.

Type
Research Article
Information
Epidemiology & Infection , Volume 115 , Issue 2 , October 1995 , pp. 309 - 314
Copyright
Copyright © Cambridge University Press 1995

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