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Prevalence of toxoplasma antibodies according to age with comments on the risk of prenatal infection

Published online by Cambridge University Press:  19 October 2009

J. van der Veen  and
M. F. Polak
J. van der Veen
Affiliation:
Laboratory for Medical Microbiology, University of Nijmegen, Nijmegen, The Netherlands
M. F. Polak
Affiliation:
Laboratory for Medical Microbiology, University of Nijmegen, Nijmegen, The Netherlands
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Sera from 1661 persons in 12 age groups from 0 to 79 years were titrated for toxoplasma antibodies in the indirect immunofluorescence test. The sera were collected from patients with symptoms suggestive of acute, mainly respiratory, viral infections. After the first year of life, the prevalence of antibodies started to rise, reaching 59% between 40 and 79 years of age. From the prevalence of antibodies in different age groups the annual infection risk, i. e. the risk of a non-immune person acquiring toxoplasma infection, was estimated for successive age periods. The estimated annual infection risk increased from 0·5% in early childhood to 3% during adolescence and early adult life.

Approximately 70–80% of females entered the age of reproduction without evidence of seroimmunity to toxoplasma. The risk of primary infection during pregnancy was estimated from the age distribution of parturient women in The Netherlands in 1975 and the age-specific incidence of primary infections, i.e. the incidence in the total population of susceptible and immune persons. This incidence of primary infection decreased from 1·62% per 9 months at the age of 17½–20 years to 0·37% at the age of 35–45 years. The incidence of primary infections in pregnant women was estimated to be 1·25%.

Type
Research Article
Information
Journal of Hygiene , Volume 85 , Issue 2 , October 1980 , pp. 165 - 174
Copyright
Copyright © Cambridge University Press 1980

References

REFERENCES

Desmonts, G. & Couvreur, J. (1974). Congenital toxoplosmosis: a prospective study of 378 pregnancies. New England Journal of Medicine 290, 1110–16.CrossRefGoogle Scholar
Desmonts, G., Couvreur, J., Alison, F., Baudelot, J., Gerbeaux, J.& Lelono, M. (1965). Etude ópidémiologiquo sur la toxoplasmoso: do l'influcnco do la cuisson dos viandos do bouchorio sur la fréquonco do l'infection humaino. Revue francaise d'Eludcs cliniquea el biologiques 10, 952–8.Google Scholar
Frenkel, J. K. (1973). Toxoplasma in and around us. Bio Science 23, 343–52.Google Scholar
Ghordani, M., Edrissiah, G. H.& Assad, N. (1978). Serological survoy of toxoplasmosis in tho northern part of Iran, using indirect fluoroscont antibody technique. Transactions of the Royal Society of Tropical Medicine and Hygiene 72, 309–71.Google Scholar
Koppe, J. G., Kloostehman, G. J., De Roever-Bonnet, H., Eckeiit-Stroink, J. A., Loewersieoer, D. H.& De Bruijne, J. I. (1974). Toxoplasmosia and pregnancy, with a long-torm follow-up of tho childron. European Journal of Obstetrics, Oynecology and Reproductive Biology 4, 101–10.CrossRefGoogle Scholar
Nunen, M. C. J. Van& Veen, J. Van Der (1905). Examination for toxoplasmosis by the fluorcscont antibody technique. Tropical and Geographical Medicine 17, 240–63.Google Scholar
Remington, J. S.& Desmonts, G. (1970). Toxoplasmosis. In Infectious diseases of the Fetus and Newborn Infant, (ed. Romington, J. S. and Kloin, J. O.), pp. 101–332. Philadelphia, London, Toronto: Saundore.Google Scholar