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Prevalence of serum IgG antibodies to Puumala virus (haemorrhagic fever with renal syndrome) in Northern Sweden

Published online by Cambridge University Press:  15 May 2009

C. Ahlm*
Affiliation:
Department of Infectious DiseasesUniversity of Umeå, Umeå, Sweden Department of VirologyUniversity of Umeå, Umeå, Sweden
M. Linderholm*
Affiliation:
Department of Infectious DiseasesUniversity of Umeå, Umeå, Sweden Department of VirologyUniversity of Umeå, Umeå, Sweden
P. Juto
Affiliation:
Department of VirologyUniversity of Umeå, Umeå, Sweden
B. Stegmayr
Affiliation:
Department of Internal Medicine, University of Umeå, Umeå, Sweden
B. Settergren
Affiliation:
Department of Infectious DiseasesUniversity of Umeå, Umeå, Sweden
*
* Address for correspondence and reprint requests: Dr Clas Ahlm, Department of Infectious Diseases. University of Umeå, S-901 85 Umeå, Sweden.
* Address for correspondence and reprint requests: Dr Clas Ahlm, Department of Infectious Diseases. University of Umeå, S-901 85 Umeå, Sweden.
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A stratified and randomly-selected population sample was identified in 1990 in order to study the seroprevalence of nephropathia epidemica (haemorrhagic fever with renal syndrome) in Northern Sweden. Sera from 1538 subjects (750 men, 788 women), 25—64 years of age, were analysed for the presence of Puumala virus (PUV) specific-IgG by the indirect immunofluorescence antibody test. Specific IgG was detected in sera from 83 subjects (5·4%). Men and women had similar seroprevalence rates. The highest seroprevalences were found in subjects 55 years or older (8·0%) and among farmers and forestry workers (15·9%). The geographic distribution of seropositive individuals was uneven and there were significantly more seropositive persons in rural than in urban areas (P < 0·05).

Type
Research Article
Copyright
Copyright © Cambridge University Press 1994

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