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Plasmid-encoded trimethoprim resistance in salmonellas isolated in Britain between 1970 and 1981

Published online by Cambridge University Press:  19 October 2009

E. J. Threlfall ,
Jennifer A. Frost ,
Hilary C. King  and
B. Rowe
E. J. Threlfall
Affiliation:
Division of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT
Jennifer A. Frost
Affiliation:
Division of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT
Hilary C. King
Affiliation:
Division of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT
B. Rowe
Affiliation:
Division of Enteric Pathogens, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT
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Summary

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Trimethoprim resistance was plasmid-encoded in all trimethoprim-resistant Salmonella typhimurium and in the majority of trimethoprim-resistant salmonellas of other serotypes isolated since 1970 from humans and food animals in Britain. In S. typhimurium, non-autotransferring plasmids of compatibility group 3 and autotransferring plasmids of group H2 predominated. The predominance of these plasmid types has resulted from the spread of clones of trimethoprim-resistant strains of phage types 18,170 and 204c. In other salmonellas, a variety of plasmid compatibility groups have been identified. Almost all plasmids which conferred resistance to trimethoprim also coded for sulphonamide resistance.

Type
Research Article
Information
Journal of Hygiene , Volume 90 , Issue 1 , February 1983 , pp. 55 - 60
Copyright
Copyright © Cambridge University Press 1983

References

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