Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-26T08:24:48.708Z Has data issue: false hasContentIssue false

The origin of urinary antibodies

Published online by Cambridge University Press:  15 May 2009

Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Antibodies to the flagellar antigens of salmonellae are frequently present in the urine of Egyptians.

2. In many individuals, who are not urinary carriers but have schistosomiasis and have received T.A.B. vaccine, these urinary antibodies are derived from the plasma due to exudation or bleeding into the urinary tract.

3. In urinary enteric carriers, the urinary antibodies are due, at least in part, to the local production or release of antibodies within the urinary tract, as shown by the ratios of urine titre to serum titre with different H suspensions.

4. The production of antibodies within the urinary tract is considered to be an example of production or liberation of antibody by cells at, or close to, the site of infection.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1953

References

Archer, G. T. L., Bangham, A. D., Dunbar, J. M. & Ritchie, A. (1950). Two urinary-carriers of enteric group organisms presenting some interesting features. J. R. Army med. Cps, 94, 302.Google Scholar
Archer, G. T. L., Goffe, A. P. & Ritchie, A. (1952). Classification of urinary carriers and the diagnostic value of urinary antibody tests. J. R. Army med. Cps, 98, 40.Google ScholarPubMed
Archer, G. T. L. & Miller, W. S. (1952). Urinary agglutinins in uninoculated chronic urinary carriers. J. R. Army med. Cps, 98, 285.Google ScholarPubMed
Burnet, F. M. & Fenner, F. (1949). The Production of Antibodies, 2nd ed., pp. 62et seq. Melbourne: Macmillan and Co. Ltd.Google Scholar
Burrows, W., Elliot, M. E. & Havens, I. (1947). Studies on immunity to Asiatic cholera. IV. The excretion of coproantibody in experimental enteric cholera in the guinea pig. J. infect. Dis. 81, 261.CrossRefGoogle Scholar
Burrows, W. & Havens, I. (1948). Studies on immunity to Asiatic cholera. V. The absorption of immune globulin from the bowel and its excretion in the urine and feces of experimental animals and human volunteers. J. infect. Dis. 82, 231.CrossRefGoogle Scholar
Davies, A. (1922). An investigation into the serological properties of dysentery stools. Lancet, ii, 1009.CrossRefGoogle Scholar
Francis, T. & Brightman, I. J. (1941). Virus-inactivating capacity of nasal secretions in the acute and convalescent stages of influenza. Proc. Soc. exp. Biol., N.Y., 48, 116.CrossRefGoogle Scholar
Harrison, P. E. & Banvard, J. (1947). Coproantibody excretion during enteric infections. Science, 106, 188.CrossRefGoogle ScholarPubMed
Horrocks, W. H. & Kennedy, J. C. (1906). Goats as a means of propagation of Mediterranean fever. Rep. Comm. Medit. Fev., part 4, p. 37.Google Scholar
Koshland, M. E. & Burrows, W. (1950). Quantitative studies of the relationship between fecal and serum antibody. J. Immunol. 65, 93.CrossRefGoogle ScholarPubMed
Miller, W. S. (1950). Some observations on enteric infection in a Delta village. J. Egypt, publ. Hlth Ass. p. 45.Google Scholar
Oakley, C. L., Batty, I. & Warrack, G. H. (1951). Local production of antibodies. J. Path. Bact. 63, 33.CrossRefGoogle ScholarPubMed
Pierce, A. E. (1947). The demonstration of an agglutinin to Trichomonas foetus in the vaginal discharge of infected heifers. J. comp. Path. 57, 84.CrossRefGoogle ScholarPubMed
Stoker, M. G. P. & Marmion, B. P. (1952). Detection of Q fever antibodies in whey by the anti-globulin sensitization test and other techniques. J. Hyg., Camb., 50, 1.CrossRefGoogle ScholarPubMed
Van Der Hoeden, J. (1935). Specifieke antistoffen in urine bij de ziekte van Weil. Ned. Tijdschr. Geneesk. 79, 1943. Summary in Bull. Hyg., Lond., 10, 447.Google Scholar
Van Der Hoeden, J. (1936). Anticorps spécifiques de la maladie de Weil dans l'urine. Ann. Inst. Pasteur, 56, 206.Google Scholar
Zammit, T. (1906). An examination of goats in Malta, with a view to ascertain to what extent they are infected with Mediterranean fever. Rep. Comm. Medit. Fev. part 4, p. 96.Google Scholar