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On the evolution of fixed strains of rabies virus

Published online by Cambridge University Press:  15 May 2009

Pierre Lépine
Pierre Lépine
Affiliation:
Rabies Department, Institut Pasteur. Paris
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We know, since the time of Pasteur, that repeated passage of rabies street virus from rabbit to rabbit after intracerebral inoculation, leads to a modification of its effect and the appearance of mutative characters. This takes place at a variable period of time depending upon the strain employed. The irreversibility and the permanence of these characters has led to the name of “fixed virus” once the street virus has become adapted for the rabbit.

Type
Research Article
Information
Journal of Hygiene , Volume 38 , Issue 2 , March 1938 , pp. 180 - 184
Copyright
Copyright © Cambridge University Press 1938

References

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