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On some Non-specific Reactions of Mallein

Published online by Cambridge University Press:  15 May 2009

H. J. Südmersen
Affiliation:
(From the Wellcome Physiological Research Laboratories, Brockwell Hall, Herne Hill, London, S.E.)
A. T. Glenny
Affiliation:
(From the Wellcome Physiological Research Laboratories, Brockwell Hall, Herne Hill, London, S.E.)
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1. Many horses immunised against other bacteria or bacterial products will give a large local reaction to mallein, but this is usually not associated with a rise in temperature. In the case of horses injected with diphtheria toxin, the size of the swelling appears to related to the degree of immunity attained. This point has not yet been established in the case of horses immunised against other bacterial products.

2. This local reaction disappears rapidly and can thus be distinguished from the reaction in the case of glandered horses.

3. In the few cases when a rise in temperature took place (3 cases out of 56) the curve was markedly different from that obtained in the case of glandered animals.

4. Other bacterial products react similarly to mallein upon immune horses.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1908

References

1 Über die Wirkung von Bakterin-Proteinen,” Zeitschr. f. Hygiene, Bd. XVIII. p. 456, 1894.Google Scholar

2 The injections were all performed by H. J. Südmersen.