Hostname: page-component-cd9895bd7-fscjk Total loading time: 0 Render date: 2024-12-22T14:58:03.141Z Has data issue: false hasContentIssue false
  • English
  • Français

Observations on the prophylaxis of experimental pulmonary anthrax in the monkey

Published online by Cambridge University Press:  15 May 2009

D. W. Henderson ,
S. Peacock  and
F. C. Belton
D. W. Henderson
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wilts.
S. Peacock
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wilts.
F. C. Belton
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wilts.
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The evidence presented supports the hypothesis that the experimental form of anthrax induced by depositing a cloud of single spores on lung epithelium is initiated in the lymphatic regions and not in lung tissue.

Proportionately few of the deposited spores reach the lymph glands. The majority remain inactive in so far as induction of disease is concerned. Slowly, however, they seem to go through the first stages of germination but do not multiply and therefore die. This is probably the major factor operative in their disappearance from the lung.

Effective prophylactic measures are suggested for dealing with an unimmunized host exposed to anthrax infection by the pulmonary route.

Type
Research Article
Information
Journal of Hygiene , Volume 54 , Issue 1 , March 1956 , pp. 28 - 36
Copyright
Copyright © Cambridge University Press 1956

References

REFERENCES

Barnes, J. M. (1947). Brit. J. exp. Path. 28, 385.Google Scholar
Belton, F. C. & Strange, R. E. (1954). Brit. J. exp. Path. 35, 144.Google Scholar
Belton, F. C., Henderson, D. W. & Peacock, S. (1956). Brit. J. exp. Path. (in the Press).Google Scholar
Druett, H. A., Henderson, D. W., Packman, L. & Peacock, S. (1953). J. Hyg., Camb., 51, 359.CrossRefGoogle Scholar
Harper, G. J. & Morton, J. D. (1953). J. Hyg., Camb., 51, 372.Google Scholar
Henderson, D. W. (1952). J. Hyg., Camb., 50, 53.CrossRefGoogle Scholar
Ross, J. (1956). J. Path. Bact. (in the Press).Google Scholar
Sterne, M. (1937). Ondestepoort J. vet. Sci. 8, 271.Google Scholar
Wright, G. G., Hedberg, Mary A. & Slein, J. B. (1954). J. Immunol. 72, 263.Google Scholar