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Mycoplasmas in cell cultures from rheumatoid synovial membranes

Published online by Cambridge University Press:  15 May 2009

K. B. Fraser ,
P. V. Shirodaria ,
Margaret Haire  and
D. Middleton
K. B. Fraser
Affiliation:
Department of Microbiology, The Queen's University of Belfast, Grosvenor Rood, Belfast, BT12 6BN
P. V. Shirodaria
Affiliation:
Department of Microbiology, The Queen's University of Belfast, Grosvenor Rood, Belfast, BT12 6BN
Margaret Haire
Affiliation:
Department of Microbiology, The Queen's University of Belfast, Grosvenor Rood, Belfast, BT12 6BN
D. Middleton
Affiliation:
Department of Microbiology, The Queen's University of Belfast, Grosvenor Rood, Belfast, BT12 6BN
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Summary

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Ten strains of myocoplasmas were recovered from cultures of synovium or cultures inoculated with synovial fragments from rheumatoid arthritis and one from osteo-arthritis. The source of the organisms is not known. Patients with rheumatoid arthritis had no complement-fixing antibody and no fluorescent staining antibody against the mycoplasmas isolated and no mycoplasma antigen was detected by immunofluorescence in sections of synovia and in synovial fluids.

The strains isolated were of two main serological types and could be distinguished by direct fluorescent antibody staining from standard types of human commensals and the common tissue-culture contaminants. One may be Mycoplasma laidlawii.

Type
Research Article
Information
Journal of Hygiene , Volume 69 , Issue 1 , March 1971 , pp. 17 - 25
Copyright
Copyright © Cambridge University Press 1971

References

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