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Mosquito-borne infections in Fiji: III. Filariasis in northern Fiji: epidemiological evidence regarding the mechanisms of pathogenesis

Published online by Cambridge University Press:  15 May 2009

J. U. Mataika ,
B. C. Dando ,
G. F. S. Spears  and
F. N. Macnamara
J. U. Mataika
Affiliation:
Medical Department, Government of Fiji, Suva, Fiji
B. C. Dando
Affiliation:
Medical Department, Government of Fiji, Suva, Fiji
G. F. S. Spears
Affiliation:
Medical School, University of Otago, Dunedin, New Zealand
F. N. Macnamara
Affiliation:
Medical School, University of Otago, Dunedin, New Zealand
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Summary

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During a filariasis survey conducted in northern Fiji in 1968–9 examinations were made for microfilaraemia, enlarged lymph nodes and elephantiasis. Analysis of the microfilarial densities at different ages and the number of anatomical sites showing lymph gland enlargement or elephantiasis have been used to provide evidence on the clustering of infections and pathogenesis.

Although there is no evidence of clustering of risk of infection, there is evidence favouring the clustering of adult filariae in individuals. Nevertheless the number of sites of lymph node enlargement do not correspond with this finding and statistical evidence suggests that lymph-node enlargement is not necessarily associated with the near presence in the body of adult filariae, whether dead or alive.

Males of Indian ethnic origin showed a higher prevalence of elephantiasis than males of Fijian ethnic origin, but women of either ethnic race showed prevalences lower than those of men.

The onset of elephantiasis at a site does not directly reflect the number of infections sustained in the local area, but it appears that filariasis first induces for a limited period a proneness to elephantiasis. During this period a random and discrete event may induce the onset of elephantiasis. The nature of the event is unknown, but it probably is not trauma.

Type
Research Article
Information
Journal of Hygiene , Volume 69 , Issue 2 , June 1971 , pp. 297 - 306
Copyright
Copyright © Cambridge University Press 1971

References

REFERENCES

Bahr, P. H. (1912). Filariasis and elephantiasis in Fiji. Journal of the London School of Tropical Medicine, supplement no. 1.Google Scholar
Beaver, P. C. (1970). Filariasis without microfilaraemia. American Journal of Tropical Medicine and Hygiene 19, 181.CrossRefGoogle Scholar
Hairston, N. G. & Jachowski, L. A. (1968). Analysis of the Wuchereria bancrofti population in the people of American Samoa. Bulletin of the World Health Organization 38, 595.Google Scholar
Hayashi, S. (1962). A mathematical analysis on the epidemiology of bancroftian and malayan filariasis in Japan. Japanese Journal of Experimental Medicine 32, 13.Google ScholarPubMed
Jordan, P. (1954). Bancroftian microfilaraemia in hospital patients. Journal of Tropical Medicine and Hygiene 57, 8.Google Scholar
Jordan, P. (1955). Observations on Wuchereria bancrofti and Acanthocheilonema perstans in Tanganyika. Transactions of the Royal Society of Tropical Medicine and Hygiene 49, 460.CrossRefGoogle ScholarPubMed
Lane, C. (1937). Bancroftian filariasis and the reticulo-endothelial system. Transactions of the Royal Society of Tropical Medicine and Hygiene 31, 61.CrossRefGoogle Scholar
Lewis, T. R. (1875). The pathological significance of nematode hematozoa. Indian Annals of Medical Science 17, 410.Google Scholar
Manson, P. (1875). Observations on lymph scrotum and allied diseases. Medical Times Gazette (London) 13 (1), 542.Google Scholar
Manson-Bahr, R. (1952). The clinical manifestations and ecology of Pacific filariasis. Documenta de Medicina geographica et tropica 4, 193.Google ScholarPubMed
Mataika, J. U., Dando, B. C., Spears, G. F. S. & Macnamara, F. N. (1971). Mosquito-borne infections in Fiji. I. Filariasis in northern Fiji: epidemiological evidence regarding factors influencing the prevalence of microfilaraemia of Wuchereria bancrofti infections. Journal of Hygiene 69, 273–86.CrossRefGoogle ScholarPubMed
Nelson, G. S. (1966). The pathology of filarial infections. Helminthological Abstracts 35, 311.Google Scholar
O'Connor, F. W. (1932). The aetiology of the disease syndrome in Wuchereria bancrofti infections. Transactions of the Royal Society of Tropical Medicine and Hygiene 26, 13.CrossRefGoogle Scholar
Schacher, J. F. & Sahyoun, P. F. (1967). A chronological study of the histopathology of filarial disease in cats and dogs caused by Brugia pahangi (Buckley & Edeson, 1956). Transactions of the Royal Society of Tropical Medicine and Hygiene 61, 234.CrossRefGoogle ScholarPubMed
Selwyn-Clarke, S. (1961). Discussion. Transactions of the Royal Society of Tropical Medicine and Hygiene 55, 132.Google Scholar
Taylor, L. R. (1961). Aggregation, variance and the mean. Nature, London 189, 732.CrossRefGoogle Scholar
Wartman, W. B. (1947). Filariasis in American armed forces in World War II. Medicine 26, 333.CrossRefGoogle ScholarPubMed
Wilson, T. (1961). Filariasis in Malaya, a general view. Transactions of the Royal Society of Tropical Medicine and Hygiene 55, 107.CrossRefGoogle Scholar
Zwart, F. A. A. G. (1968). Report on the census of the population (1966). Govt. of Fiji Council Paper no. 9, 1968.Google Scholar