Hostname: page-component-6bf8c574d5-2jptb Total loading time: 0 Render date: 2025-02-18T00:14:54.835Z Has data issue: false hasContentIssue false
  • English
  • Français

A modified haemagglutination inhibition test for rubella antibodies, using standardized, freeze-dried reagents. Report of a comparative multi-centre trial

Published online by Cambridge University Press:  15 May 2009

Bauke K. van Weemen  and
Jovan Kacaki
Bauke K. van Weemen
Affiliation:
Organon Scientific Development Group, Oss, The Netherlands
Jovan Kacaki
Affiliation:
Organon Scientific Development Group, Oss, The Netherlands
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A modified haemagglutination inhibition test for rubella antibodies, using standardized freeze-dried reagents, was developed and compared with haemagglutination inhibition tests using fresh erythrocytes. This comparison was made in collaboration with six European laboratories. A total of 4205 serum samples were tested. The results show that:

(1) Sensitivity and reliability of the modified test are good;

(2) the modified test can be performed in glass tubes as well as in polystyrene microtitration plates.

Type
Research Article
Information
Journal of Hygiene , Volume 77 , Issue 1 , August 1976 , pp. 31 - 42
Copyright
Copyright © Cambridge University Press 1976

References

REFERENCES

Gispen, R., Huisman, J., Brand-Saathof, B. & Hekker, A. C. (1974). Immunofluorescence test for persistent pox virus antibodies. Archiv für die gesamte Virusforschung 44, 391–5.Google Scholar
Gregg, N. M. (1941). Congenital cataract following German measles in the mother. Transactions of the Ophthalmological Society of Australia 3, 35–46.Google Scholar
Gupta, J. D. & Harley, J. D. (1970). Use of formalinized sheep erythrocytes in the rubella haemagglutination inhibition test. Applied Microbiology 20, 843–4.CrossRefGoogle Scholar
Inouye, S. & Kono, R. (1972). Effect of a modified kaolin treatment on serum immunoglobulins. Applied Microbiology 23, 203–6.Google Scholar
Meyer, H. M. Jr., Parkman, P. D. & Hopps, H. E. (1972). The clinical application of laboratory diagnostic procedures for rubella and measles (rubeola). American Journal of Clinical Pathology 57, 803–13.Google Scholar
Norrby, E. (1962). Haemagglutination by measles virus. 4. A simple procedure for production of high potency antigen for haemagglutination inhibition tests. Proceedings of the Society for Experimental Biology and Medicine 111, 814–18.CrossRefGoogle Scholar
Schuurs, A. H. W. M.de Jager, E. & Homan, J. D. H. (1968). Studies on human chorionic gonadotrophin. Acta endocrinologica 59, 120–38.Google Scholar
Stewart, G. L., Parkman, P. D., Hopps, H. E., Douglas, R. D., Hamilton, J. P. & Meyer, H. M. Jr. (1967). Rubella virus haemagglutination inhibition test. New England Journal of Medicine 276, 554–7.CrossRefGoogle Scholar
Wide, L. (1962). An immunologic method for the assay of human chorionic gonadotrophin. Acta endocrinologica Suppl. 70, 20–27.Google Scholar