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Microbiology of HIV associated bacteraemia and diarrhoea in adults from Nairobi, Kenya

Published online by Cambridge University Press:  15 May 2009

B. I. F. Batchelor ,
J. N. Kimari  and
R. J. Brindle
B. I. F. Batchelor
Affiliation:
Kenya Medical Research Institute, PO Box 43640, Nairobi, Kenya Public Health Laboratory Service, John Radcliffe Hospital, Oxford, OX3 9DU, UK
J. N. Kimari
Affiliation:
Kenya Medical Research Institute, PO Box 43640, Nairobi, Kenya
R. J. Brindle*
Affiliation:
Kenya Medical Research Institute, PO Box 43640, Nairobi, Kenya Public Health Laboratory Service, John Radcliffe Hospital, Oxford, OX3 9DU, UK
*
* Author for correspondence
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We undertook a retrospective descriptive comparison of the spectrum of pathogens responsible for bacteraemia and diarrhoea in HIV antibody positive and negative patients over 4 years (1988–92), in Nairobi, Kenya. The study population was recruited from primary to tertiary centers of clinical care and consisted of 2858 adults (15 years or older). There were 415 significant blood culture isolates, 192 from 1785 HIV negative patients and 223 from 953 HIV positive patients. There were 233 significant faecal isolates, 22 from 115 HIV negative patients and 211 from 531 HIV positive patients. The most common pathogens detected in blood were Streptococcus pneumoniae and Salmonella typhimurium and in faeces Shigella flexneri, S. typhimurium and Cryptosporidium parvum. The agents causing illness in HIV positive patients in Nairobi are similar to those prevalent in the HIV negative community and the investigation of a febrile illness with or wothout diarrhoea in an HIV positive patient should reflect this.

Type
Research Article
Information
Epidemiology & Infection , Volume 117 , Issue 1 , August 1996 , pp. 139 - 144
Copyright
Copyright © Cambridge University Press 1996

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