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Method used to identify previously undiagnosed infections in the HIV outbreak at Glenochil prison

Published online by Cambridge University Press:  01 October 1999

S. J. HUTCHINSON ,
S. M. GORE ,
D. J. GOLDBERG ,
D. L. YIRRELL ,
J. MCGREGOR ,
A. G. BIRD  and
A. J. LEIGH-BROWN
S. J. HUTCHINSON
Affiliation:
Scottish Centre for Infection and Environmental Health, Clifton House, Clifton Place, Glasgow G3 7LN, UK
S. M. GORE
Affiliation:
MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
D. J. GOLDBERG
Affiliation:
Scottish Centre for Infection and Environmental Health, Clifton House, Clifton Place, Glasgow G3 7LN, UK
D. L. YIRRELL
Affiliation:
Centre for HIV Research, University of Edinburgh, Kings Buildings, Edinburgh, UK
J. MCGREGOR
Affiliation:
Scottish Prison Service, HMP Glenochil, UK
A. G. BIRD
Affiliation:
Department of Immunology, Churchill Hospital, Oxford, UK
A. J. LEIGH-BROWN
Affiliation:
Centre for HIV Research, University of Edinburgh, Kings Buildings, Edinburgh, UK
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Abstract

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Four years after the occurrence of an outbreak of hepatitis B and HIV infection among injecting drug user inmates at Her Majesty's Prison Glenochil in Scotland, a study design was developed to complete the epidemiological account of the HIV outbreak. Our aim was to identify potential cases of (1) HIV transmission not diagnosed during the original outbreak investigation and (2) the source(s) of the outbreak. Scotland's HIV positive case register was searched for matches to a soundexed list of 636 Glenochil inmates imprisoned during January–June 1993. Eight HIV infections that may have been acquired in Glenochil and four possible sources of the outbreak were identified. The second stage of follow-up – molecular epidemiological techniques used on stored sera samples from identified individuals – is described in the companion paper. Without breach of medical or prisoner confidentiality, indirect and anonymous follow-up has proved possible for the Glenochil inmates.

Type
Research Article
Information
Epidemiology & Infection , Volume 123 , Issue 2 , October 1999 , pp. 271 - 275
Copyright
© 1999 Cambridge University Press