Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-22T15:29:03.009Z Has data issue: false hasContentIssue false
  • English
  • Français

A method for preparing smallpox vaccine on a large scale in cultured cells*

Published online by Cambridge University Press:  15 May 2009

C. Kaplan  and
Lisel R. Micklem
C. Kaplan
Affiliation:
Lister Institute of Preventive Medicine, Elstree, Hertfordshire
Lisel R. Micklem
Affiliation:
Lister Institute of Preventive Medicine, Elstree, Hertfordshire
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A tissue culture system using chick embryo cells gave bacteria-free vaccinia virus suspensions of sufficient potency to use as a vaccine. Clinical trials with vaccines prepared by this method gave similar results to those with sheep lymph vaccine.

Type
Research Article
Information
Journal of Hygiene , Volume 59 , Issue 2 , June 1961 , pp. 171 - 180
Copyright
Copyright © Cambridge University Press 1961

References

REFERENCES

Bland, J. O. W. & Robinow, C. F. (1939). J. Path. Bact. 48, 381.CrossRefGoogle Scholar
Bodlan, D. (1956). Virology, 2, 575.Google Scholar
Buddingh, C. J. (1943). Amer. J. Hyg. 38, 310.Google Scholar
Buddingh, C. J. & Randall, C. C. (1951). Amer. J. Hyg. 53, 152.Google Scholar
Carrel, A. & Rivers, T. M. (1927). C.R. Soc. Biol., Paris, 96, 848.Google Scholar
Cook, E. B. M., Crain, P. N. & Irons, J. V. (1948). Publ. Hlth Lab. 6 (05), 50.Google Scholar
Cutchins, E. & Warren, J. (1957). Fed. Proc. 16, 410.Google Scholar
Dulbecco, R. & Vogt, M. (1954). J. exp. Med. 99, 167.CrossRefGoogle Scholar
Eagles, G. H. & McClean, D. (1929). Brit. J. exp. Path. 10, 35.Google Scholar
Earle, W. R. (1943). J. nat. Cancer Inst. 4, 167.Google Scholar
Earle, W. R., Sanford, K. K., Evans, V. J., Waltz, H. K. & Shannon, J. E. (1951). J. nat. Cancer Inst. 12, 133.Google Scholar
Feller, A. E., Enders, J. F. & Weller, T. H. (1940). J. sup. Med. 72, 367.Google Scholar
Fiscker, A. & Jenson, A. B. (1946). Acta physiol. scand. 12, 218.Google Scholar
Goodpasture, E. W. & Buddingh, G. J. (1933). Science, 78, 484.CrossRefGoogle Scholar
Goodpasture, E. W. & Buddingh, G. J. (1935). Amer. J. Hyg. 21, 319.Google Scholar
Irons, J. V. & Cook, E. B. M. (1957). Bol. Ofic. sanit. pan-amer. 42, 138.Google Scholar
Kaltenbach, J. P., Kaltenbach, M. H. & Lyons, W. B. (1958). Exp. Cell Res. 15, 112.CrossRefGoogle Scholar
Kapsenberg, J. G. (1955). Het Kweken van Vaccinia-Virus in Geëxplanteerd Weefsel. Amsterdam: Diligentia Publishing Co.Google Scholar
Li, C. P. & Rivers, T. M. (1930). J. exp. Med. 52, 465.CrossRefGoogle Scholar
Mackie, T. J. & McCartney, J. E. (1948). Handbook of Practical Bacteriology, 8th ed., Edinburgh: E. and S. Livingstone Ltd.Google Scholar
McIlvaine, T. C. (1921). J. biol. Chem. 49, 183.CrossRefGoogle Scholar
Maitland, H. B. & Maitland, M. C. (1928). Lancet, ii, 596.CrossRefGoogle Scholar
Nagler, F. P. O. (1944). Aust. J. eup. Biol. med. Sci. 22, 29.CrossRefGoogle Scholar
Noyes, W. B. & Watson, B. K. (1955). J. exp. Med. 102, 237.CrossRefGoogle Scholar
Pandit, C. G. (Oct. 1941–Mar. 1946). Rep. King Inst. prev. Med. Guindy, India.Google Scholar
Periera, H. G. (1954). J. gen. Microbiol. 10, 500.CrossRefGoogle Scholar
Ramon, G., Richon, R., Thiery, J.-P., Salomon, L. & Salomon, L. (1953). C.R. Acad. Sci., Paris, 236, 2033.Google Scholar
Ramon, G., Richon, R., Thiery, J.-P., Salomon, L. & Salomon, L. (1954 a). C.R. Acad. Sci., Paris, 238, 29.Google Scholar
Ramon, C., Richon, R., Thiery, J.-P., Salomon, L. & Doucet, M.P. (1954 b). Rev. Immunol. 18, 1–20.Google Scholar
Rappaport, L. M. (1956). Bull. World Hlth Org. 14, 147.Google Scholar
Rivers, T. M., Ward, S. M. & Baird, R. D. (1939). J. exp. Med. 69, 857.CrossRefGoogle Scholar
Robbins, F. C. & Enders, J. F. (1950). Amer. J. med. Sci. 220, 316.Google Scholar
Robinow, C. F. (1950). J. gen. Microbiol. 4, 242.CrossRefGoogle Scholar
Sanford, K. K., Earle, W. R. & Likely, G. B. (1948). J. nat. Cancer Inst. 9, 229.Google Scholar
Stevenson, W. D. H. & Butler, G. G. (1933). Lancet, ii, 228.Google Scholar
Stevenson, W. D. H. & Butler, G. G. (1934). Bull. Off. int. Hyg. Publ. 26, 64.Google Scholar
Stevenson, W. D. H. & Butler, G. G. (1935). Bull. Off. int. Hyg. Publ. 27, 48.Google Scholar
Stevenson, W. D. H. & Butler, G. G. (1939). Rep. publ. Hlth med. Subj., Lond., no. 87.Google Scholar
Wesslén, T. (1953). Atti. VI Congr. int. Microbiol. Roma, 3 (viii), 66.Google Scholar
Wesslén, T. (1956). Arch. ges. Virusforsch. 6, 430.CrossRefGoogle Scholar
Westwood, J. C. N., MacPherson, I. A. & Titmuss, D. H. I. (1957). Brit. J. exp. Path. 38, 138.Google Scholar
Westwood, J. C. N., Phipps, P. H. & Boulter, E. A. (1957). J. Hyg., Camb. 55, 123.Google Scholar