Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-25T19:53:15.187Z Has data issue: false hasContentIssue false
  • English
  • Français

Meningococcal infections in Scotland 1972–82

Published online by Cambridge University Press:  19 October 2009

R. J. Fallon ,
W. M. Brown  and
W. Lore
R. J. Fallon
Affiliation:
Departments of Laboratory Medicine and Infectious Diseases, Ruchill Hospital, Glasgow G20 9NB, Scotland
W. M. Brown
Affiliation:
Departments of Laboratory Medicine and Infectious Diseases, Ruchill Hospital, Glasgow G20 9NB, Scotland
W. Lore
Affiliation:
Departments of Laboratory Medicine and Infectious Diseases, Ruchill Hospital, Glasgow G20 9NB, Scotland
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Strains of Neisseria meningitidis isolated from patients with meningitis or septicaemia without meningitis in Scotland during the years 1972–82 have been reviewed together with details of the age, sex, disease and outcome of the patients from whom they were isolated. A total of 1185 strains were isolated, of which 927 were examined at the Meningococcal Reference Laboratory (Scotland): 19·3% were of serogroup A, 63% of group B, 9·6% of group C, 6% of W135 and 1·6% of other groups. Non-groupable strains were rare. Disease was most common in the first years of life but there was a difference in the age distribution of disease due to the different serogroups, the proportion of disease due to group B being smaller in adults than that due to other serogroups. The overall mortality in meningitis was 7·5% and in septicaemia was 20·6%, although there were differences between the rates for the various serogroups. The serogroup distribution differed in disease as opposed to meningococci isolated from carriers although group B strains were predominant in both series. Overall, approximately 15% of strains were resistant to sulphadiazine, the proportion of resistant group A strains being higher than that of other serogroups.

Type
Research Article
Information
Journal of Hygiene , Volume 93 , Issue 2 , October 1984 , pp. 167 - 180
Copyright
Copyright © Cambridge University Press 1984

References

Andersen, B. M. (1978). Mortality in meningococcal infections. Scandinavian Journal of Infectious Diseases 10, 277–282.CrossRefGoogle ScholarPubMed
Band, J. D., Chamberland, M. E., Platt, T., Weaver, R. E., Thornsberry, C. & Fraser, D. W. (1983). Trends in meningococcal disease in the United States, 1975–1980. Journal of Infectious Diseases 148, 754–758.CrossRefGoogle ScholarPubMed
Bjorvatn, B., Bjertnaes, L., Fadnes, H. O.Flaegstad, T., Gutteberg, T. J., Kristiansen, B-E., Pape, J., Rekvig, O. P., Osterud, B. & Aanderud, L. (1984). Meningococcal septicaemia treated with combined plasmapheresis and leucapheresis or with blood exchange. British Medical Journal 288, 439–441.Google Scholar
Bohr, V., Hansen, B., Jessen, O., Johnsen, N., Kjersem, H., Kristensen, H. S., Nyboe, J. & Rasmussen, N. (1983 a). Eight hundred and seventy-five cases of bacterial meningitis. Part I of a three part series: clinical data, prognosis, and the role of specialised hospital departments. Journal of Infection 7, 21–30.CrossRefGoogle ScholarPubMed
Bohr, V., Hansen, B., Kjersem, H., Rasmussen, N., Johnsen, N., Kristensen, H. S. & Jessen, O. (1983 b). Sequelae from bacterial meningitis and their relation to the clinical condition during acute illness, based on 667 questionnaire returns. Part II of a three part series. Journal of Infection 7, 102–110.CrossRefGoogle Scholar
Bol, P., Spanjaard, L., de Marie, S. & Zanen, H. C. (1983). 500 strains of Neisseria meningitidis. What happened to the hosts? Médecine Tropicale 43, Hors serie no. 1, pp. 90–91.Google Scholar
Danielsson, D. & Olcén, P. (1979). Rapid serotyping of groups A, B and C meningococci by rocket-line immunoelectrophoresis and co-agglutination. Journal of Clinical Pathology 32, 136–142.CrossRefGoogle Scholar
Davey, P. G., Cruickshank, J. K., McManus, I. C., Mahood, B., Snow, M. H., & Geddes, A. M. (1983). Bacterial meningitis – ten years experience. Journal of Hygiene Camb 88, 383–400.CrossRefGoogle Scholar
De Marie, S. & Zanen, H. C. (1983). Differences in severity and prognosis of meningococcal disease related to serogroup. Medecine Tropicale 43, hors serie no. 1, pp. 21–24.Google Scholar
Devine, L. F. & Hagerman, C. R. (1970). Relationship of serogroups of Neisseria meningitidis. I. Microngglutination, gel diffusion and slide agglutination studies of meningococcal antisera before and after absorption with RAS-10 strain of meningococci. Infection and Immunity 1, 226–231.CrossRefGoogle ScholarPubMed
Evans-Jones, L. G., Whittle, H. C., Onyewotu, I. I., Egler, L. J. & Greenwood, B. M. (1977). Comparative study of group A and group C meningococcal infection. Archives of Disease in Childhood 52, 320–323.CrossRefGoogle Scholar
Fallon, R. J. (1976). The relationship between Neisseria meningitidis of serogroups Z1 and 29E. Journal of Medical Microbiology 9, 239–242.CrossRefGoogle ScholarPubMed
Fallon, R. J. (1978). Meningococci. In Laltoratory Methods in Antimicrobial Chemotherapy (ed. Reeves, , Phillips, , Williams, and Wise, ), pp. 99–102. Edinburgh: Churchill Livingstone.Google Scholar
Frasch, C. E.& Chapman, S. S. (1972 a). Classification of Neisseria meningitidis group B into distinct serotypes. II. Extraction of type-specific antigens for serotyping by precipitation techniques. Infection and Immunity 6, 127–133.CrossRefGoogle Scholar
Frasch, C. E. & Chapman, S. S. (1972 b). Classification of Neisseria meningitidis group B into distinct serotypes. I. Serological tvping bv a bactericidal method. Infection and Immunity 5, 98–102.CrossRefGoogle Scholar
Frasch, C. E. & Chapman, S. S. (1973). Classification of Neisseria meningitidis into distinct serotypes. III. Application of a new bactericidal-inhibition technique to distribution of serotypes among cases and carriers. Journal of Infectious Diseases 127, 140–154.Google Scholar
Galaid, E. I., Cherubim, C. E., Marr, J. S., Schaefler, S., Barone, J. & Lee, W. (1980). Meningococcal disease in New York City 1973 to 1978. Journal of the American Medical Association 244, 2167–2171.CrossRefGoogle ScholarPubMed
Gold, R. & Wyle, F. A. (1970). New classification of Neisseria meningitidis by means of bactericidal reactions. Infection and Immunity 1, 479–484.CrossRefGoogle ScholarPubMed
Goldacre, M. J. (1976). Acute bacterial meningitis in childhood. Incidence and mortality in a defined population. Lancet i, 28–31.CrossRefGoogle Scholar
Irwin, R. S., Woelk, W. K. & Coudon, W. L. III. (1975). Primary meningococcal pneumonia. Annals of Internal Medicine 82, 493–498.CrossRefGoogle ScholarPubMed
Jones, D. M. & Eldridoe, J. (1981). Meningococcal disease in England and Wales 1978–9 – a change in the serotype pattern. Journal of Infection 3, 134–139.CrossRefGoogle Scholar
Meningococcal Disease Surveillance Group (1976). Analysis of endemic meningococcal disease by serogroup and evaluation of chemo-prophylaxis. Journal of Infectious Diseases 134, 201–204.CrossRefGoogle Scholar
Moss, P. D. (1982). Outcome of meningococcal group B meningitis. Archives of Disease in Childhood 57, 616–621.CrossRefGoogle ScholarPubMed
Peltola, H. (1983). Meningococcal disease: still with us. Reviews of Infectious Diseases 5, 71–91.CrossRefGoogle ScholarPubMed
Peltola, H., Jónsdóttir, K., Lystad, A., Sievers, C. J. & Kallings, I. (1982). Meningococcal disease in Scandinavia. British Medical Journal 284, 1618–1621.CrossRefGoogle ScholarPubMed
Peltola, H., Kataja, J. M. & Mäkelä, P. H. (1982). Shift in the age-distribution of meningococcal disease as a predictor of an epidemic? Lancet ii, 595–597.CrossRefGoogle Scholar
Report (1981). Surveillance of meningococcal meningitis: France. WHO Weekly Epidemiological Record 56, 225–226.Google Scholar
Report (1982). Bacterial Meningitis in the Netherlands: Annual Report, 1982. Laboratory of Hygiene, University of Amsterdam.Google Scholar
Sivonen, A., Renkonen, O.-V. & Robbins, J. B. (1977). Use of antiserum agar plates for serogrouping of meningococci. Journal of Clinical Pathology 30, 834–837.CrossRefGoogle ScholarPubMed
Yee, N. M., Katz, M. & Neu, H. C. (1975). Meningitis, pneumonitis and arthritis caused by Neisseria meningitidis group Y. Journal of the American Medical Association 232, 1354–1355.CrossRefGoogle ScholarPubMed
Young, H., Harris, A. B., Robertson, D. H. H. & Fallon, R. J. (1983). Ano-genital gonorrhoea and pharyngeal colonisation with meningococci: a serogroup analysis. Journal of Infection 6, 49–54.CrossRefGoogle ScholarPubMed