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Legionella infections in Scotland

Published online by Cambridge University Press:  25 March 2010

R. J. Fallon
R. J. Fallon
Affiliation:
Department of Laboratory Medicine, Ruchill Hospital, Glasgow, G20 9NB
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Four thousand two hundred and thirty-five sera from 2794 patients and 740 sera from 735 tourists domiciled in Scotland recently returned from abroad were examined between 1977 and 1981 for antibodies to Legionella pneumophila and related organisms. In addition, specimens were examined from some patients for cultural or serological demonstration of these organisms in lung or sputum. One hundred and ten cases were diagnosed, 104 serologically, five by immunofluorescence demonstration of legionellas in lung biopsy or autopsy specimens and L. pneumophila serogroup 1 was isolated from a further case. Of patients with pneumonia 6·7% showed evidence of legionella infection. Only 0·4% of healthy tourists had antibodies at a level of ⋝ 256. The majority of cases occurred in patients aged 50–69 and in 36 patients the infection was acquired outside the United Kingdom. Males predominated, the male: female ratio being 2:1. Cases were less frequent in the first quarter of the year but those originating in Scotland were equally common in the remaining three quarters. Cases with disease acquired abroad added to indigenous cases resulted in a summer peak occurring in July, August and September. There were no outbreaks of legionellosis in Scotland.

Type
Research Article
Information
Journal of Hygiene , Volume 89 , Issue 3 , December 1982 , pp. 439 - 448
Copyright
Copyright © Cambridge University Press 1982

References

REFERENCES

Bartlett, C. L. R. cited by Reid, D. (1981). Epidemiology of legionellosis. Nederlands Tijdschrift Voor Geneeskund 25, 1268.Google Scholar
Boyd, J. F., Buchanan, W. M., MacLeod, T. I. F., Shaw Dunn, R. I. & Weir, W. P. (1978). Pathology of five Scottiah deaths from pneumonic illnesses acquired in Spain due to Legionnaires' disease agent. Journal of Clinical Pathology 31, 809–816.CrossRefGoogle ScholarPubMed
Cherry, W. B., McKinney, R. W. (1978). In ‘Legionnaires’: the disease, the bacterium and methodology, (ed. Jones, G. L. and Hebert, G. A.). Atlanta: Centers for Disease Control.Google Scholar
England, A. C. iii, Fraser, D. W., Pilikaytis, B. D., Tsai, T. F., Storch, G. & Broome, C. V. (1981). Sporadic legionellosis in the United States: the first thousand cases. Annals of Internal Medicine 94, 164–170.CrossRefGoogle ScholarPubMed
Fallon, R. J. (1981). Laboratory diagnosis of Legionnaires' Disease. ACP Broadsheet 99.Google Scholar
Fallon, R. J. & Abraham, W. H. (1978). Legionnaires' disease. Lancet 2, 1318.CrossRefGoogle ScholarPubMed
Fallon, R. J. & Abraham, W. H. (1979). Scottish experience with the serologic diagnosis of Legionnaires' disease. Annals of Internal Medicine 90, 684–6.CrossRefGoogle ScholarPubMed
Fallon, R. J. & Abraham, W. H. (1982). Polyvalent heat-killed antigen for the diagnosis of infection with Legionella pneumophila. Journal of Clinical Pathology 35, 434–438.CrossRefGoogle ScholarPubMed
Harrison, T. G. & Taylor, A. G. (1982). Diagnosis of Legionella pneumophila infections by meants of formalised yolk sac antigens. Journal of Clincial Pathology 35, 211–214.CrossRefGoogle Scholar
Horwitz, M. A. & Silverstein, S. C. (1980). Legionnaires' disease bacterium (Legionella pneumophila) multiplies intracellularly in human monocytes. Journal of Clinical Investigation 66. 441–50.CrossRefGoogle Scholar
Lawson, J. HL (1978). Legionnaires' disease – the Benidorm episode. Scottish Medical Journal 23, 121–124CrossRefGoogle ScholarPubMed
Lees, A. W., Tyrrkll, W. F. & Boyd, J. F. (1977). Legionnaires' disease. Lancet 2, 1187.CrossRefGoogle Scholar
McDade, J. F., Shepard, C. C., Fraser, D. W., Tsai, T. R., Redus, M. A., Dowdle, W. A. & the laboratory investigation team (1977). Legionnaires' disease. Isolation of a bacterium and demonstration of its role in other respiratory disease. New England Journal of Medicine 297. 1197–203.CrossRefGoogle ScholarPubMed
Macrae, A. D., Appleton, P. N. & Laverick, A. (1979). Legionnaires' disease in Nottingham England. Annals of Internal Medicine 90, 580–583.CrossRefGoogle ScholarPubMed
Reid, D., Grist, N. R. & Najera, R. (1978). Illness associated with ‘package tours’: a combined Spanish-Scottish study. Bulletin of the World Health Organisation 56, 117–122.Google Scholar
Snowman, W. R., Holtzhauer, F. J., Halpin, T. J. & Correa-Villasenor, A. (1982). The role of indoor and outdoor occupations in the seroepidemiology of Legionella pneumophila. Journal of Infectious Diseases 145, 275.CrossRefGoogle ScholarPubMed
Tobin, J.O'H., Bartlett, C. L. R., Waitkins, S. A., Barrow, G. I., Macrae, A. D., Taylor, A. G., Fallon, R. J. & Lynch, F. R. N. (1981). Legionnaires' disease: further evidence to implicate water storage and distribution systems as sources. British Medical Journal 282, 573.CrossRefGoogle ScholarPubMed
Wilkinson, H. W., Fikes, B. J. & Cruce, D. D. (1979). Indirect immunofluorescence test for serodiagnosis of Legionnaires' disease. Evidence for serogroup diversity of Legionnaires' disease bacterial antigens and for multiple specificity of human antibodies. Journal of Clinical Microbiology 9, 379–83.CrossRefGoogle ScholarPubMed