Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-22T15:35:52.851Z Has data issue: false hasContentIssue false
  • English
  • Français

Laboratory evaluation of scilliroside used as a rodenticide against the lesser bandicoot rat, Bandicota bengalensis

Published online by Cambridge University Press:  19 October 2009

Joe E. Brooks  and
Pe Than Htun
Joe E. Brooks
Affiliation:
Rodent Control Demonstration Unit, World Health Organization, PO Box 14, Rangoon, Burma
Pe Than Htun
Affiliation:
Rodent Control Demonstration Unit, World Health Organization, PO Box 14, Rangoon, Burma
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The toxicity and efficacy of the acute rodenticide scilliroside was evaluated in the laboratory against the lesser bandicoot rat, Bandicota bengalensis. The acute oral LD50 and LD 95 doses for males were 0·8 mg/kg and 2·5 mg/kg respectively, and for females were 0·5 mg/kg and 1·6 mg/kg, respectively. When caged bandicoots were given a choice between plain and poison baits, the optimum concentration of scilliroside was found to be 0·05%. Symptoms of poisoning appear from 22 to 34 min after feeding starts and the latency pattern indicated an abrupt ceasing to feed at these points. Death occurred from 2 h to as long as 6 days after poisoning, following prolonged convulsive seizures. There appears to be aversion to scilliroside at all concentrations in food baits. Maximum mortality attained on free-choice feeding on scilliroside was 90%. Despite these disadvantages, the material may have merit as an alternative rodenticide to zinc phosphide where acute toxicants are to be used.

Type
Research Article
Information
Journal of Hygiene , Volume 85 , Issue 2 , October 1980 , pp. 227 - 234
Copyright
Copyright © Cambridge University Press 1980

References

REFERENCES

Barnett, S. A., Blaxland, J. D., Leech, F. B. & Spencer, M. M. (1949). A conccntrato of rod squill as n rnt poison, and itn toxicity to domestic animals. Journal of Hygiene 47, 431–3.Google Scholar
Brooks, J. E. & Htun, P. T. (1978). Laboratory evaluation of pyriminyl used as a rodenticido against tho lessor bandicoot rat, Bandicota bcngalensis. Journal of Hygiene 80, 401–8.CrossRefGoogle Scholar
Crabtree, D. G., Ward, J. C. & Welch, J. F. (1939). Sex differences in albino rats to toxic dosago of powdored red squill. Endocrinology 25, 629–32.CrossRefGoogle Scholar
Dieke, S. H. & Richter, C. P. (1946). Comparative assays of rodenticides on wild Norway rats. I. Toxicity. Public Health Reports, Washington 61, 672–9.CrossRefGoogle Scholar
Dybing, F., Dybing, O. & Stormorken, H. (1952). The toxicity of red squill and scillirosido to rats and mico. Ada pharmacologica et toxicologica 8, 301–0.Google Scholar
Htun, P. T. & Brooks, J. E. (1979). Laboratory ovaluation of tho toxicity and ofllcacy of zinc phosphido used as a rodenticido against tho lesser bandicoot rat, Bandicota bcngalensis. Pesticides Abstracts and News Summary 25, 240–50.Google Scholar
Litchfield, J. T. & Wilcoxon, F. (1949). A simplified method of ovaluating doso-effect oxporiments. Journal of Pharnuxcology and Experimental Therapeutics 96, 99–113.Google Scholar
Maddock, D. R. & Schoof, H. F. (1970). Now rod squill dorivativo: laboratory and field studios on stabilized scillirosido against Norway rats. Pest Control 38, 22–24, 35, 45–40.Google Scholar
Ogushi, K. & Tokumitso, I. (1972). Studios on rodenticides, VI. Feeding preferences of Norway rats for scillirosido baits and lothal doses of tho baits. Japanese Journal of Sanitary Zoology 23, 71–5.Google Scholar
Pollitzer, R. (1954). Plague. WHO Monograph, Geneva, 698 pp.Google Scholar
Prosser, P. R. & Karam, J. H. (1978). Diabotcs mellitus following rodenticido ingestion in man. Journal of the American Medical Association 239, 1148–50.CrossRefGoogle ScholarPubMed
Redfern, R. (1971). Techniquo for oral intubation of wild rats. Laboratory Animals 5, 100–72.CrossRefGoogle ScholarPubMed
Rothlin, E. & Schalch, W. R. (1952). Pharmakologio und Toxikologio von Scillirosid und Scillirosidin. Helvetia physiologica et pharmacologica acta. 10, 427–37.Google Scholar
Stoll, A. (1954). Sur lea sunstancos cardiotoniques do la scillo maritimo (Scilla maritima L.). Experientia, 10, 282–97.CrossRefGoogle Scholar
Stoll, R. & Renz, J. (1961). Uebor Scillirosid, oin gegon Nagor spocifisch wirksames Gift dor roton Meerzwiobel. Helvetia chimica acta 25, 43–64.CrossRefGoogle Scholar
Stoll, R. & Renz, J. (1942). Der Lactonring des Scillirosids. Helvetia chimica acta 25, 377–91.CrossRefGoogle Scholar
Stoll, R., Renz, J. & Helfenstein, A. (1943). Uobor dio Struktur doa Scillirosids. Helvetia chimica acta 26, 648–72.CrossRefGoogle Scholar
Tanaka, I. (1973). Evaluation of rodonticides as a tracking powder. Japanese Journal of Sanitary Zoology 23, 219–23.Google Scholar