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Laboratory evaluation of pyriminyl used as a rodenticide against the lesser bandicoot rat, Bandicota bengalensis*

Published online by Cambridge University Press:  15 May 2009

Joe E. Brooks  and
Pe Than Htun
Joe E. Brooks
Affiliation:
Rodent Control Demonstration Unit, World Health Organization, Rangoon, Burma
Pe Than Htun
Affiliation:
Rodent Control Demonstration Unit, World Health Organization, Rangoon, Burma
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The properties of pyriminyl (N-3-pyridylmethyl-N′-p-nitrophenyl urea) as a rodenticide against the lesser bandicoot rat (Bandicota bengalensis) in Rangoon, Burma, were investigated in the laboratory. The acute LD 50 and LD 95 dose of orally administered pyriminyl for B. bengalensis were found to be 6·7 mg/kg and 23·0, mg/kg of body weight respectively. When caged bandicoots were given a choice between plain and poisoned baits, the optimum rodenticidal concentration in the bait was found to be 0·25–0·5%. Symptoms of pyriminyl poisoning appear from 1 to 4 h after feeding starts, giving individual animals time to consume from 2 to over 30 LD 50 doses of 0·5% pyriminyl before feeding stops. Deaths occurred from 4 to 96 h after either oral dosing or free-choice feeding. There appeared to be no significant aversion to the poison at 0·25% or 0·5% concentration in foods. The potential hazards and use of pyriminyl as a field bait against populations of B. bengalensis are discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 80 , Issue 3 , June 1978 , pp. 401 - 408
Copyright
Copyright © Cambridge University Press 1978

References

REFERENCES

Barnett, S. A., Cowan, P. E., Radford, G. G. & Prakash, I. (1975). Peripheral anosmia and the discrimination of poisoned food by Rattus rattus L. Behavioural Biology 13, 183–90.CrossRefGoogle ScholarPubMed
Barnett, S. A. & Prakash, I. (1975). Rodents of Economic Importance in India. New Delhi: Arnold-Heinemann. 175 pp.Google Scholar
Bhatnagar, J. K. (1966). Role of rodents in plague epidemiology in Uttar Pradesh. In Indian Rodent Symposium,Calcutta,8–11 December, 1966, pp. 204–15. Johns Hopkins University Centre for Medical Research and Training.Google Scholar
Brooks, J. E., U Hla, Naing, Walton, D. W., Daw San, Myint, U Maung, Maung Tun, U, Thaung & Daw Ohn, Kyi (1977). Plague in small mammals and humans in Rangoon, Burma. South-east Asian Journal of Tropical Medicine and Public Health 8, 335–44.Google ScholarPubMed
Chemical and Engineering News (1975). Rat poison does deed in only one feeding. 24 March 1975, pp. 8.Google Scholar
Cowan, P. E., Srihari, K. & Sridhara, S. (1977). Toxicity of a new rodenticide, Vacor, to lesser bandicoot rats, Bandicota bengalensis. Current Science. 46, 453–4.Google Scholar
Deoras, P. J. (1965). A note on the trial of two modern ratticides. Current Science 34, 348–9.Google Scholar
Deoras, P. J. (1968). Simple methods in rat reduction on 186 villages in Panvel. In International Symposium on Bionomics and Control of Rodents,Kanpur, pp. 153–8.Google Scholar
Deoras, P. J. (1969). Significance of probable change of rat population in Bombay. In Indian Rodent Symposium,Calcutta,8–11 December, 1966, pp. 58–68. Johns Hopkins University Centre for Medical Research and Training.Google Scholar
Harrison, J. L. & Woodville, H. C. (1948). An attempt to control house rats in Rangoon. Transactions of the Royal Society of Tropical Medicine and Hygiene 42, 247–58.CrossRefGoogle Scholar
Harrison, J. L. & Woodville, H. C. (1950). Notes on the feeding habits of house rats in Rangoon. Annals of Applied Biology 37, 296–304.CrossRefGoogle Scholar
Hood, G. A. (1972). Zinc phosphide – a new look at an old rodenticide for field rodents. Proceedings of the Fifth Vertebrate Pest Conference,Fresno, California,7–9 March 1972, pp. 85–92.Google Scholar
Kapoor, I. P., Ramisivan, R. T. & Krishnamurthy, K. (1965). Evaluation of Shoxin as a rodenticide. Bulletin of Grain Technology 3, 160–2.Google Scholar
Litchfield, J. T. & Wilcoxon, F. (1949). A simplified method of evaluating dose-effect experiments. Journal of Pharmacology and Experimental Therapeutics 96, 99–113.Google ScholarPubMed
Muktabai, K., Krishnakumari, M. K. & Mujumder, S. K. (1968). Magnesium ammonium arsenate as rodenticide. In International Symposium on Bionomics and Control of Rodents,Kanpur, pp. 118–19.Google Scholar
Parrack, D. W. (1969). A note on the loss of food to the lesser bandicoot rat, Bandicota bengalensis. Current Science 35, 544–5.Google Scholar
Peardon, D. L. (1974). RH-787 – new selective rodenticide. Pest Control 42 (9), 14, 16, 18, 27.Google Scholar
Rao, R. S. (1947). Role of field rats in plague. Indian Medical Gazette 82, 96–101.Google ScholarPubMed
Redfern, R. (1971). Technique for oral intubation of wild rats. Laboratory Animals 5, 169–72.CrossRefGoogle ScholarPubMed
Schoof, H. F. (1970). Zinc phosphide as a rodenticide. Pest Control 38 (5), 38, 42–4.Google Scholar
Seal, S. C. & Banerji, R. N. (1969). Changing patterns of rodent population in Calcutta and Howra, In Indian Rodent Symposium,Calcutta,8–11 December, 1966, pp. 69–83. Johns Hopkins University Centre for Medical Research and Training.Google Scholar
Simpson, G. G., Roe, A. & Lewontin, R. C. (1960). Quantitative Zoology, 440 pp. New York: Harcourt, Brace and World.Google Scholar
Spillett, J. J. (1968). The Ecology of the Lesser Bandicoot Rat in Calcutta, 223 pp. Bombay: Leaders Press Private Ltd.Google Scholar
Srivastava, A. S., Tripathi, R. S., Pandya, R. C. & Awasthi, G. P. (1968). Investigations on the toxicity of barium carbonate and zinc phosphide to field rats. In International Symposium on Bionomics and Control of Rodents,Kanpur, pp. 80–3.Google Scholar
Walton, D. W., Brooks, J. E., U Maung, Maung Tun & U Hla, Naing (1977). The status of Rattus norvegicus in Rangoon, Burma. Japanese Journal of Sanitary Zoology. (In the Press.)Google Scholar
Whitmoyer Laboratories (1975a). Toxicity information for poison control centres. 2 pp. mimeo.Google Scholar
Whitmoyer Laboratories (1975b). Animal toxicity and treatment information for a new family of rodenticide componds. 4 pp. mimeo.Google Scholar