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Published online by Cambridge University Press: 15 May 2009
Since Green & Mellanby (1928, 1930) reported that vitamin A protected the body against infection, this problem has been studied by various authors (Verder, 1928; Lassen, 1930, 1931; Seidmon & Arnold, 1931–2; Boynton & Bradford, 1931; McClung & Winters, 1932; Stryker & Janota, 1941). In general, the results showed that A avita-minotic animals were more susceptible to spontaneous or experimental infections than controls kept on a normal diet. However, in so far as we know, no experimental work has been done on the inverse problem—the effect of infection on vitamin A metabolism.