Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-19T14:50:16.216Z Has data issue: false hasContentIssue false
  • English
  • Français

Infectivity of Pasteurella tularensis clouds

Published online by Cambridge University Press:  15 May 2009

A. M. Hood
A. M. Hood
Affiliation:
Microbiological Research Establishment, Porton Down, Salisbury, Wilts.
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The infectivity of Pasteurella tularensis clouds decreases with age, for guineapigs challenged by the peritoneal and respiratory routes. No decrease occurs in mice challenged peritoneally. The loss of infectivity depends to some extent on age of culture but more especially on culture medium used. Cultures grown in a partially hydrolysed casein medium and aged 2–3 weeks lose infectivity severely in clouds held 20 hr. at 85% r.h., whereas if grown in cysteine broth with catalase (CBC) no loss occurs in this time until cultures are aged several months. Chloride ion, yeast extract and casein hydrolysate are shown to be infectivity depressors when used in culture media or when added to suspensions before spraying. Sodium chloride in CBC can be replaced adequately by sodium sulphate or sodium phosphate for growth of the organism.

Type
Research Article
Information
Journal of Hygiene , Volume 59 , Issue 4 , December 1961 , pp. 497 - 504
Copyright
Copyright © Cambridge University Press 1961

References

Goldberg, L. J., Watkins, H. M. S., Boerke, E. E. & Chatigny, M. A. (1958). Amer. J. hyg. 68, 85.Google Scholar
Guyton, A. C. (1947). Amer. J. Physiol. 150, 70.CrossRefGoogle Scholar
Harper, G. J. & Morton, J. D. (1953). J. Hyg., Camb., 51, 372.CrossRefGoogle Scholar
Harper, G. J., Hood, A. M. & Morton, J. D. (1958). J. Hyg., Camb., 56, 364.CrossRefGoogle Scholar
Henderson, D. W. (1952). J. Hyg., Camb., 50, 53.CrossRefGoogle Scholar
Hood, A. M. (1961). J. gen. microbiol. 26, 45.CrossRefGoogle Scholar
Mills, R. C., Berthelsen, H., Donaldson, D. & Wilhelm, P. L. (1949). Bact. Proc. p. 37.Google Scholar
May, K. R. & Harper, G. J. (1957). Brit. J. industr. Med. 14, 287.Google Scholar
Peto, S. (1953). Biometrics, 9, 3.CrossRefGoogle Scholar
Pirsch, G. W., Day, W. C., Bailey, R. R. & Griffith, W. R. (1959). Bact. Proc. p. 100.Google Scholar
Schlamm, N. A., Goldberg, L. J. & Dimmick, R. C. (1959). Bact. Proc. p. 100.Google Scholar
Schlamm, N. A. (1960). J. Bact. 80, 818.CrossRefGoogle Scholar