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The incidence of Herpesvirus hominis antibody in the population

Published online by Cambridge University Press:  15 May 2009

Isabel W. Smith
Affiliation:
Department of Bacteriology, University of Edinburgh
J. F. Peutherer
Affiliation:
Department of Bacteriology, University of Edinburgh
F. O. MacCallum
Affiliation:
The Radcliffe Infirmary, Oxford
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Sera from 1029 individuals, 864 from Edinburgh and 165 from Oxford, have been examined for the presence of antibodies to Herpesvirus hominis. The results of the smaller Oxford survey did not reveal a higher incidence of antibody where direct comparison was possible with those from Edinburgh.

The incidence of both complement-fixing and neutralizing antibodies in the sera from 710 people in Edinburgh with ages varying from 1 month to 92 years was compared with the more complete of the earlier surveys, and in particular with that of Holzel et al. (1953) in Manchester, England. This comparison revealed a lower incidence of antibody in people under 25 in Edinburgh in 1965.

Results obtained with sera from medical students in Oxford and Edinburgh and from nurses in Edinburgh were in agreement with those of previous surveys. The low incidence of antibody in these young people emphasized the possible occupational risk of infection from patients and that primary herpetic infection might be encountered more frequently than before in teenagers and young adults.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1967

References

REFERENCES

Anderson, S. G. & Hamilton, J. (1949). The epidemiology of primary herpes simplex. Med. J. Aust. i, 308.CrossRefGoogle Scholar
Andrewes, C. H. & Carmichael, E. A. (1930). A note on the presence of antibodies to herpes virus in postencephalitic and other human sera. Lancet i, 857.CrossRefGoogle Scholar
Andrews, B. E. & McDonald, J. C. (1955). Influenza virus C infection in England. Br. med. J. ii, 992.CrossRefGoogle Scholar
Ashe, W. K. & Scherp, H. W. (1963). Antigenic analysis of herpes simplex virus by neutralization kinetics. J. Immun. 91, 658.CrossRefGoogle ScholarPubMed
Ashe, W. K. & Scherp, H. W. (1965). Antigenic variations in herpes simplex virus isolants from successive recurrences of herpes labialis. J. Immun. 94, 385.CrossRefGoogle ScholarPubMed
Becker, W. B. (1966). The epidemiology of herpesvirus infection in three racial communities in Cape Town. S. Afr. med. J. 40, 109.Google Scholar
Buddingh, G. J., Schrum, D. I., Lanier, J. C. & Guidry, D. J. (1953). Studies on the natural history of herpes simplex infections. Pediatrics, Springfield 11, 595.CrossRefGoogle ScholarPubMed
Burnet, F. M. & Williams, S. W. (1939). Herpes simplex: a new point of view. Med. J. Aust. i, 637.CrossRefGoogle Scholar
Coetzee, J. N. (1955). The epidemiology of herpes simplex in the Pretoria Bantu population. S. Afr. J. Lab. clin. Med. i, 52.Google Scholar
Dascomb, H. E., Adair, C. V. & Rogers, N. (1955). Serologic investigations of herpes simplex virus infections. J. Lab. clin. Med. 46, 1.Google ScholarPubMed
Eilard, U. & Hellgren, L. (1965). Herpes simplex. Dermatologica 130, 101.CrossRefGoogle ScholarPubMed
Gold, J. A., Stewart, R. C. & McKee, J. (1965). The epidemiology and chemotherapy of herpes simplex keratitis and herpes simplex skin infections. Ann. N.Y. Acad. Sci. 130, 209.CrossRefGoogle ScholarPubMed
Grist, N. R., Ross, C. A. C., Bell, E. J. & Stott, E. J. (1966). Diagnostic Methods in Clinical Virology, pp. 64, 99. Oxford: Blackwell Scientific Publications.Google Scholar
Halonen, P. (1955). Investigations on the virus of herpes simplex. The herpes simplex complement-fixation test and its use in the study of herpes antibodies. Anns Med. exp. Biol. Fenn. 33, suppl. 9.Google Scholar
Hayward, M. E. (1949). Serological studies with herpes simplex virus. Br. J. exp. Path. 30, 520.Google Scholar
Holzel, A., Feldman, G. V., Tobin, J. O'H. & Harper, J. (1953). Herpes simplex; a study of complement-fixing antibodies at different ages. Acta Paediat., Stockh. 42, 206.CrossRefGoogle ScholarPubMed
Jones, B. (1959). The management of ocular herpes. Trans. ophthal. Soc. U.K. 79, 425.Google ScholarPubMed
Kapsenberg, J. G. (1964). Possible antigenic relationship between varicella zoster virus and herpes simplex virus. Arch. ges. Virusforsch. 15, 67.CrossRefGoogle ScholarPubMed
Kibrick, S. & Gooding, G. W. (1965). Pathogenesis of infection with herpes simplex virus with special reference to nervous tissue. National Institute Neurological Diseases of Blindness. Monograph No. 2, Slow, Latent and Temperate Virus Infections, p. 143.Google Scholar
MacCallum, F. O. (1959). Generalised herpes simplex in the neonatal period. Acta virol., Prague 3, (suppl.) 17.Google Scholar
Macpherson, I. & Stoker, M. (1962). Polyoma transformation of hamster cell clones—an investigation of genetic factors affecting cell competence. Virology 16, 147.CrossRefGoogle ScholarPubMed
Murray, E. S., Gaon, J. A., O'Connor, J. M. & Mulahasanović, M. (1965). Serologic studies of primary epidemic typhus and recrudescent typhus (Brill-Zinsser disease). J. Immun. 94, 723.CrossRefGoogle ScholarPubMed
Peutherer, J. F. & Smith, I. W. (1966). The use of an accelerated adsorption method in a quantal estimation of the infectivity of Herpesvirus hominis. J. Path. Bact. 92, 230.CrossRefGoogle Scholar
Rodrigues, M. C. & Carvalho, R. P. de S. (1965). Estudo da distribuição etãria de anticorpos neutralizantes contra o virus do herpes simples em São Paulo. Revta Inst. Med. trop. S. Paulo 7, 323.Google Scholar
Ross, C. A. C., Subak, Sharpe J. H. & Ferry, P. (1965). Antigenic relationship of varicella-zoster and herpes simplex. Lancet ii, 708.CrossRefGoogle Scholar
Stern, H., Elek, S. D., Millar, D. M. & Anderson, H. F. (1959). Herpetic whitlow. A form of cross-infection in hospitals. Lancet ii, 871.CrossRefGoogle Scholar
Taglieri, G. & Tresca, G. (1964). Rilievi siero-epidemiologici in nn campione della popolazione dell' Asmara (Eritrea). Archo ital. Sci. med. trop. Parassit. 45, 209.Google Scholar
Weyer, E. R. (1932). Herpes antiviral substances: distribution in various age groups and apparent absence in individuals susceptible to poliomyelitis. Proc. Soc. exp. Biol. Med. 30, 309.CrossRefGoogle Scholar
Yoshino, K., Taniguchi, S., Furuse, R., Nojima, T., Fujii, R., Minamitani, M., Tada, R. & Kubota, H. (1962). A serological survey for antibodies against herpes simplex virus with special reference to comparatively heat-labile complement-fixing antibodies. Jap. J. med. Sci. Biol. 15, 235.CrossRefGoogle Scholar
Zinsser, H. & Tang, F. F. (1929). Further experiments on the agent of herpes. J. Immun. 17, 343.CrossRefGoogle Scholar