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In vitro and in vivo study of fosfomycin in methicillin-resistant Staphylococcus aureus septicaemia

Published online by Cambridge University Press:  19 October 2009

W. Y. Lau ,
C. H. Teoh-Chan ,
S. T. Fan  and
K. F. Lau
W. Y. Lau
Affiliation:
Government Surgical Unit, Queen Mary Hospital
C. H. Teoh-Chan
Affiliation:
Department of Microbiology, University of Hong Kong
S. T. Fan
Affiliation:
Government Surgical Unit, Queen Mary Hospital
K. F. Lau
Affiliation:
Department of Microbiology, University of Hong Kong
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Summary

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Five hundred strains of methicillin-resistant Staphylococcus aureus were tested against various anti-staphylococcal agents. Vancomycin, fusidic acid and fosfomycin were found to be the most effective. Only 1 strain out of 500 was resistant to fosfomycin. Three patients with methicillin-resistant Staphylococcus aureus septicaemia were successfully treated by fosfomycin. We conclude that fosfomycin could be the drug of choice for methicillin-resistant Staphylococcus aureus infection.

Type
Research Article
Information
Journal of Hygiene , Volume 96 , Issue 3 , June 1986 , pp. 419 - 423
Copyright
Copyright © Cambridge University Press 1986

References

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