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The impact of physico-chemical stress on the toxigenicity of Vibrio cholerae

Published online by Cambridge University Press:  19 October 2009

Christopher J. Miller ,
Bohumil S. Drasar ,
Richard G. Feachem  and
Richard J. Hayes
Christopher J. Miller
Affiliation:
Department of Tropical Hygiene, London School of Hygiene and Tropical Medicine
Bohumil S. Drasar
Affiliation:
Department of Medical Microbiology, London School of Hygiene and Tropical Medicine
Richard G. Feachem
Affiliation:
Department of Tropical Hygiene, London School of Hygiene and Tropical Medicine
Richard J. Hayes
Affiliation:
Tropical Epidemiology Unit, London School of Hygiene and Tropical Medicine
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Summary

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The expression of toxigenicity by Vibrio cholerae, before and after exposure to various conditions of salinity, pH and cation composition and concentration, has been measured. Exposure to these conditions did not select for hyper- or hypo-toxigenic strains. This suggests that toxigenic V. cholerae O 1 are unlikely to lose their toxigenicity when exposed to environmental stress and that V. cholerae toxin production is not a response to the stresses included in this study. These results are consistent with an aquatic reservoir for toxigenic V. cholerae O 1.

Type
Research Article
Information
Journal of Hygiene , Volume 96 , Issue 1 , February 1986 , pp. 49 - 57
Copyright
Copyright © Cambridge University Press 1986

References

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