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Immunization to Vi and O Antigens of Salmonella Typhi Using a Stable Antigen in Oil

Published online by Cambridge University Press:  15 May 2009

David C. Y. Chu ,
Robert E. Hoyt  and
M. J. Pickett
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A method is described for the preparation of a vaccine, consisting of a suspension of bacterial cells in a vegetable oil, which retains the antigenic activity of both Vi and O antigens of S. typhi. The ability of such a vaccine to induce active and passive protection in mice is demonstrated.

Type
Research Article
Information
Journal of Hygiene , Volume 54 , Issue 4 , December 1956 , pp. 592 - 596
Copyright
Copyright © Cambridge University Press 1956

References

Chu, C. Y. & Hoyt, R. E. (1954). Reactions of T Vi and Ballerup Vi haptenes with antisera against Vi-coated erythrocytes. J. Hyg., Camb., 52, 100–5.Google Scholar
Chu, C. Y., Hoyt, R. E. & Pickett, M. J. (1956). Solubility of Vi antigen of Salmonella typhi. J. Hyg., Camb., 54, 585.Google ScholarPubMed
Felix, A. (1941). A new type of typhoid and paratyphoid vaccine. Brit. med. J. 1, 391–5.CrossRefGoogle ScholarPubMed
Felix, A. (1951). The preparation, testing and standardization of typhoid vaccine. J. Hyg., Camb., 49, 268–87.Google Scholar
Freund, J. (1951). The effect of paraffin oil and mycobacteria on antibody formation and sensitization. Amer. J. clin. Path. 21, 645–56.Google Scholar