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Identification of pregnancies at risk from cytomegalovirus infection

Published online by Cambridge University Press:  15 May 2009

L. M. de Silva ,
G. L. Kampfner ,
C. M. Lister  and
J. O.'H. Tobin
L. M. de Silva
Affiliation:
Public Health Laboratory, Withington Hospital, Manchester, M20 8LR
G. L. Kampfner
Affiliation:
Public Health Laboratory, Withington Hospital, Manchester, M20 8LR
C. M. Lister
Affiliation:
Public Health Laboratory, Withington Hospital, Manchester, M20 8LR
J. O.'H. Tobin
Affiliation:
Public Health Laboratory, Withington Hospital, Manchester, M20 8LR
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The fluorescent antibody technique was used for the identification of specific cytomegalovirus IgM in the sera of twenty-four of 1065 unmarried pregnant women. Seventeen of them were followed to term and five infected infants were identified. Two other infants had CMV IgM in neonatal serum samples but virus excretion was not demonstrated. The congenital infection rate in this study was 5·3 per 1000 births by virus excretion and 7·9 per 1000 if cases with specific IgM are included; from previous studies a rate of 8·8 per 1000 was expected. The reasons for the lack of relationship between specific IgM in the mothers' serum and infected babies is discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 79 , Issue 3 , December 1977 , pp. 347 - 354
Copyright
Copyright © Cambridge University Press 1977

References

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