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Heat labile and heat stable factors and antibodies in normal and immune sera against T-system bacteriophages

Published online by Cambridge University Press:  15 May 2009

Enver Tall Çetin
Enver Tall Çetin
Affiliation:
The London School of Hygiene and Tropical Medicine*
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1. Heat labile and heat stable inactivating factors against T-system phages are present in normal guinea-pig and rabbit sera. These may be antibodies.

2. Sera of guinea-pigs immunized with phages T2, T3 and T4 contain heat labile and heat stable antibodies.

3. The heat labile activity is absorbed from guinea-pig serum by phage more readily than the heat stable activity.

4. Dilution of the sera reduces the heat labile activity more than the heat stable activity.

5. Complement has no effect on the inactivation or neutralization of phages T2, T3 and T4 by normal or immune guinea-pig sera.

Type
Research Article
Information
Journal of Hygiene , Volume 58 , Issue 1 , March 1960 , pp. 35 - 43
Copyright
Copyright © Cambridge University Press 1960

References

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