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Growth, toxigenicity and virulence of Pseudomonas aeruginosa

Published online by Cambridge University Press:  15 May 2009

Pinghui V. Liu  and
Charles B. Mercer
Pinghui V. Liu
Affiliation:
Department of Microbiology, University of Louisville School of Medicine, Louisville, Kentucky
Charles B. Mercer
Affiliation:
Department of Microbiology, University of Louisville School of Medicine, Louisville, Kentucky
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The virulence of Pseudomonas aeruginosa appears to depend on both its ability to grow in the serum of animals and its ability to produce various types of extra-cellular toxins. No strain of Ps. aeruginosa lacking either of these qualifications was ever found to be virulent to animals.

The ability of various sera of animals to inhibit growth of Ps. aeruginosa appears to depend largely on their content of specific antibodies to each serological type of the surface antigens (the slime layer) and, therefore, susceptibility of animals to the infections of Ps. aeruginosa, even within one species, varies considerably from one individual to another.

This work was supported by a research career development award of the U.S. Public Health Service to the senior author (GM-K3–15).

Type
Research Article
Information
Journal of Hygiene , Volume 61 , Issue 4 , December 1963 , pp. 485 - 491
Copyright
Copyright © Cambridge University Press 1963

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