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Genetic factors in leprosy: a study of children in Uganda

Published online by Cambridge University Press:  15 May 2009

Susan J. White ,
M. Mary Stone  and
C. Howland
Susan J. White
Affiliation:
M.R.C. Statistical Research and Services Unit, 115 Gower Street, London, WC1E 6AS
M. Mary Stone
Affiliation:
M.R.C. Statistical Research and Services Unit, 115 Gower Street, London, WC1E 6AS
C. Howland
Affiliation:
M.R.C. Statistical Research and Services Unit, 115 Gower Street, London, WC1E 6AS
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Summary

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A group of 20 990 children in Uganda was examined for leprosy over a period of 8 years. There was no evidence that the incidence of leprosy varied according to a child's genetic relationship to a leprosy patient, once allowance had been made for the grade of physical contact.

Type
Research Article
Information
Journal of Hygiene , Volume 80 , Issue 2 , April 1978 , pp. 205 - 216
Copyright
Copyright © Cambridge University Press 1978

References

REFERENCES

Beiguelman, B. (1972). An appraisal of genetic studies on leprosy. Acda geneticae medicae et gemellologiae 21, 21–52.CrossRefGoogle Scholar
Brown, J. A. K. (1955). The incidence and epidemiology of leprosy in Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene 49, 241–52.CrossRefGoogle ScholarPubMed
Brown, J. A. K. (1957). The epidemiology of leprosy. East African Medical Journal 34, 351–60.Google ScholarPubMed
Brown, J. A. K. (1959). Factors influencing the transmission of leprosy. International Journal of Leprosy 27, 250–60.Google Scholar
Brown, J. A. K. & Stone, M. M. (1966). BCG vaccination of children against leprosy: first results of a trial in Uganda. British Medical Journal i, 7–14.CrossRefGoogle Scholar
Brown, J. A. K., Stone, M. M. & Sutherland, I. (1968). BCG vaccination of children against leprosy: results at end of second follow-up. British Medical Journal i, 24–27.CrossRefGoogle Scholar
Chakravartti, M. R. & Vogel, F. (1973). A twin study on leprosy. In Topics in Human Genetics, vol. I (ed. Becker, P. E., Lenz, W., Vogel, F. and Wendt, G. G.). Stuttgart: Georg Thieme.Google Scholar
Cochran, W. G. (1954). Some methods for strengthening the common χ2 tests. Biometrics 10, 417–51.CrossRefGoogle Scholar
Daniellsen, D. C. & Boeck, W. (1848). Traité de la Spédalskhead ou Eléphantiasis des Grecs. (French translation by Cosson, L. A..) Paris: Baillière. Quoted in Beiguelman, 1972.Google Scholar
De Vries, R. R. P., Lai, A., Fat, R. F. M., Nijenhuis, L. E. & Van Rood, J. A. (1976). HLA-linked genetic control of host response to Mycobacterium leprae. Lancet ii, 1328–30.CrossRefGoogle Scholar
Mohamed-Ali, P. & Ramanujam, K. (1966). Leprosy in twins. International Journal of Leprosy 34, 405–7.Google Scholar
Newell, K. W. (1966). An epidemiologist's view of leprosy. Bulletin of the World Health Organization 34, 827–57.Google ScholarPubMed
Spickett, S. G. (1962). Genetics and the epidemiology of leprosy, II. The form of leprosy. Leprosy Review 33, 173–181.Google ScholarPubMed
Spickett, S. G. (1964). Genetic mechanisms in leprosy. In Leprosy in Theory and Practice (ed. Cochran, R. G., Davey, T. F. and McRobert, Sir George), pp. 98–124. Bristol: John Wright.Google Scholar
Thomas, M. & Job, C. K. (1972). Serum atypical pseudocholinesterase and genetic factors in leprosy. British Medical Journal iii, 390–91.CrossRefGoogle Scholar
Vogel, F. (1968). ABO blood groups and leprosy. Journal of Medical Genetics 5, 56–7.CrossRefGoogle ScholarPubMed
World Health Organization (1970). WHO Expert Committee on Leprosy, Fourth Report, p. 24. Technical Report Series, No. 459, Geneva.Google Scholar