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The first cycle of growth in the chick embryo of the agents of trachoma and inclusion blennorrhoea

Published online by Cambridge University Press:  15 May 2009

P. Reeve
Affiliation:
M.R.C. Trachoma Research Unit, The Lister Institute of Preventive Medicine, London, S. W. 1
Janice Taverne
Affiliation:
M.R.C. Trachoma Research Unit, The Lister Institute of Preventive Medicine, London, S. W. 1
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Chick embryos were inoculated with measured doses of various strains of the agents of trachoma and inclusion blennorrhoea, and the number of infective organisms they contained was determined at intervals during the first 4 days after inoculation. From curves of the yield of agent at different times relative to the dose inoculated, it was evident that the lag phase before the exponential phase of growth began was shorter for fast-killing—and more virulent—variant strains than for slow-killing strains, and the difference was statistically significant; and that variant strains multiplied faster during the exponential phase of growth and produced then- highest titres sooner.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1967

References

Collier, L. H. (1963). Nomenclature of isolates of virus from trachoma and inclusion blennorrhoea. Nature, Lond. 198, 1229.CrossRefGoogle ScholarPubMed
Collier, L. H. & Sowa, J. (1958). Isolation of trachoma virus in embryonate eggs. Lancet i, 993.CrossRefGoogle Scholar
Gear, J. H. S., Gordon, F. B., Jones, B. R. & Bell, S. D. Jun. (1963). Nomenclature of isolates of virus from trachoma and inclusion blennorrhoea. Nature, Lond. 197, 26.CrossRefGoogle Scholar
Jawetz, E. & Hanna, L. (1960). Trachoma viruses isolated in the United States. 2. Assay of egg infectivity and stability. Proc. Soc. exp. Biol. Med. 105, 207.CrossRefGoogle ScholarPubMed
Jones, B. R. (1961). TRIC virus infections in London. Trans. ophthal. Soc. U.K. 81, 367.Google Scholar
Murray, E. S., Bell, S. D. Jun., Hanna, A. T., Nichols, R. L. & Snyder, J. C. (1960). Studies on trachoma. 1. Isolation and identification of strains of elementary bodies from Saudi Arabia and Egypt. Am. J. trop. Med. Hyg. 9, 116.CrossRefGoogle ScholarPubMed
Reed, L. J. & Muench, H. (1938). A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27, 493.Google Scholar
Reeve, P. & Taverne, J. (1963). Observations on the growth of trachoma and inclusion blennorrhoea viruses in embryonate eggs. J. Hyg., Camb. 61, 67.CrossRefGoogle Scholar
T'ang, F. F., Chang, H. L., Huang, Y. T. & Wang, K. C. (1957). Studies on the etiology of trachoma with special reference to the isolation of the virus in chick embryos. Chin. med. J. 75, 49.Google Scholar
Taverne, J., Blyth, W. A. & Reeve, P. (1964). Growth in the chick embryo of strains of trachoma and inclusion blennorrhoea virus of differing virulence. J. gen. Microbiol. 37, 277.CrossRefGoogle ScholarPubMed