Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-05T08:03:24.258Z Has data issue: false hasContentIssue false
  • English
  • Français

Factors associated with Paracoccidiodes brasiliensis infection among permanent residents of three endemic areas in Colombia

Published online by Cambridge University Press:  15 May 2009

D. Cadavid  and
A. Restrepo
D. Cadavid
Affiliation:
Mycology Section, Corporacion para Investigaciones Biologicas (CIB), Hospital Pablo Tobon Uribe, Apartado Aereo 7378, Medellin, Colombia, S.A.
A. Restrepo*
Affiliation:
Mycology Section, Corporacion para Investigaciones Biologicas (CIB), Hospital Pablo Tobon Uribe, Apartado Aereo 7378, Medellin, Colombia, S.A.
*
* Author for correspondence and reprint requests.
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The natural habitat of Paracoccidioides brasiliensis, the aetiologic agent of paracoccidioidomycosis, has not been determined. Consequently, the events leading to the acquisition of infection remain controversial. To identify factors associated with infection in endemic areas we conducted a survey in three rural communities in Colombia where we had previously diagnosed paracoccidioidomycosis in children. Permanent residents were surveyed taking into consideration environmental and occupational variables. Skin tests were used to classify subjects as infected or non-infected. Variables found associated with infection were: (i) community A: previous residence around Porce river and agriculture in vegetable gardens; (ii) community C: frequent use of specific water sources; (iii) community V: housekeeping activities, and (iv) total group: age > 25 years and contact with bats. Residents in communities with higher prevalence of infection were older, had more complex residence history, and referred more contact with armadillos than residents of communities with lower infection.

Type
Research Article
Information
Epidemiology & Infection , Volume 111 , Issue 1 , August 1993 , pp. 121 - 133
Copyright
Copyright © Cambridge University Press 1993

References

1.Borelli, D. Prevalence of systemic mycoses in Latin America. In: Proceedings of the International Symposium on Mycoses: PAHO, 1970; Publ. No. 205: 28–38.Google Scholar
2.Ajello, L. Comparative ecology of respiratory mycotic agents. Bacteriol Rev 1967; 31: 6'24.Google Scholar
3.Restrepo, A. The ecology of Paracoccidiodes brasiliensis: a puzzle still unsolved. J Med Vet Mycol 1985; 23: 323'34.CrossRefGoogle Scholar
4.Albornoz, M. Isolation of P. brasiliensis from rural soil in Venezuela. J Med Vet Mycol 1971; 9: 248'53.CrossRefGoogle Scholar
5.Borelli, D. Some ecological aspects of paracoccidiodomycosis. In: Proceedings Panamerican Symposium Paracoccidiodomycosis. Washington, D.C.: PAHO, 1972; Publ. No. 254: 59–64.Google Scholar
6.Londero, A. Epidemiologia. In: Paracoccidiodomycosis (South American Blastomycosis), Del, Negro G, Calacaz, CS, Fiorillo, AM, eds. São Paulo: Sarvier, 1982: 85–90.Google Scholar
7.Restrepo, A, Greer, D, Moncada, H. Relationship between the environment and paracoccidiodomycosis. In: Proceedings Panamerican Symposium Paracoccidiodomycosis. Washington, D.C.: PAHO, 1972; Publ. No. 254: 84–91.Google Scholar
8.Borelli, D. Concepto de reservarea de la paracoccidiodomicosis. Dermatol Venez 1963–1964; 4: 71–7.Google Scholar
9.Pereira, A, Barbosa, W. Inquerito intradermico paracoccidioidomicose in Goiania, Brasil. Rev Patol Trop 1988; 17: 157–86.Google Scholar
10.Restrepo, A., Robledo, M, Ospina, S, et al. Distribution of paracoccidiodin sensitivity in Colombia. Am J Trop Med Hyg 1968; 17: 25–39.Google Scholar
11.Lacaz, C, Porto, E, Martinez, J, eds. Micologia Medica: Fungos, actinomicetos e algas de interesse medico. São Paulo: Sarvier, 1991: 248–61.Google Scholar
12.Greer, D, Restrepo, A. The epidemiology of Paracoccidiodomycosis. In: The epidemiology of human mycotic diseases, Doory, YA, ed. Springfield: C. C. Thomas, 1975: 273–82.Google Scholar
13.Naiff, R, Ferreira, LCL, Barret, T. Enzootic paracoccidiodomycosis in armadillos (D. novemcincuts) in the State of Para. Rev Inst Med Trop São Paulo 1986; 28: 19–27.CrossRefGoogle Scholar
14.Mos, E, Fava-Netto, C. Contribucao ao estudo de paracoccidioidomicose. I Possivel papel epidemiologica dos caes. Rev Inst Med Trop São Paulo 1974; 16: 154–9.Google Scholar
15.Grose, E, Tamsitt, J. p. brasiliensis recoved from the intestinal tract of 3 bats (A. lituratus) in Colombia. J Med Vet Mycol 1965; 4: 124–5.CrossRefGoogle Scholar
16.Gezuele, E. Aislamiento de Paracoccidioides sp. de heces de pinguino de la Antártida. Proceedings IV International Meeting on Paracoccidioidomycosis. Caracas, 1989: Abstract B2.Google Scholar
17.Buckley, C. III. Delayed hypersensitivity skin testing. In: Manual of clinical laboratory immunology, Rose, NR, Friedman, H, eds. 3rd ed. Washington, D.C.: American Society for Microbiology, 1986: 260–73.Google Scholar
18.Restrepo, A, Schneidau, J. Nature of the skin-reactive principle in culture filtrates prepared from Paracoccidioides brasiliensis. J Bacteriol 1967; 93: 1741–8.CrossRefGoogle Scholar
19.Budnick, L. Statistics. In: Preventive medicine and public health. Cassens, BJ, ed. Philadelphia: John Wiley & Sons, 1987: 62–7.Google Scholar
20.Krause, M. Food, nutrition and diet therapy: a textbook of nutritional care. 7th ed. WB Saunders & Co., 1984: 956–62.Google Scholar
21.Utz, J. Histoplasmosis. In: Infectious diseases, Hoeprich, PD, ed. Philadelphia: Harper and Row, 1983: 451–52.Google Scholar
22.Wheat, L.. Histoplasmosis in Indianapolis. Clin Inf Dis 1992; 14: S91–9.CrossRefGoogle ScholarPubMed
23.Klein, B, Vergeront, J, Weeks, R, et al. Isolation of Blastomyces dermatitidis in soil associated with a large outbreak of blastomycosis in Wisconsin. N Engl J Med 1986; 314: 529–34.CrossRefGoogle ScholarPubMed
24.Klein, B, Vergeront, J, DiSalvo, A, Kaufman, L, Davis, J. Two outbreaks of blastomycosis along rivers in Wisconsin: isolation of Blastomyces dermatitids from riverbank soil and evidence of its transmission along waterways. Am Rev Respir Dis 1987; 136: 133–8.Google Scholar
25.Bradsher, R. Blastomycosis. Clin Inf Dis 1992; 14: S82–90.CrossRefGoogle ScholarPubMed
26.Greer, D, Bolaños, B. Role of bats in the ecology of P. brasiliensis. The survival of P. brasiliensis in the intestinal tract of the fructivorous bat A. lituratus. J Med Vet Mycol 1977; 15: 273–82.Google Scholar