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The experimental transformation of variola to vaccinia

Published online by Cambridge University Press:  15 May 2009

E. S. Horgan
E. S. Horgan
Affiliation:
Stack Medical Research Laboratories, Khartoum
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1. The more recent literature on the experimental methods employed in variola or alastrim-vaccinia variation is reviewed and briefly discussed.

2. An account is given of attempts to produce a vaccinia variant from variola of the virulent type and a successful result, by employing the method of intratesticular passage, has been described.

3. The reasons for accepting this as a genuine variation and not a vaccinial contamination are discussed.

4. An attempt has been made to analyse some possible factors underlying the discrepancies in the literature, and a plea is made for more co-operation in future work on the subject.

Type
Research Article
Information
Journal of Hygiene , Volume 38 , Issue 6 , November 1938 , pp. 702 - 715
Copyright
Copyright © Cambridge University Press 1938

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