Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-25T00:33:57.428Z Has data issue: false hasContentIssue false
  • English
  • Français

Experimental infection of Rhesus monkeys with a human strain of Campylobacter jejuni

Published online by Cambridge University Press:  25 March 2010

R. B. Fitzgeorge ,
A. Baskerville  and
K. P. Lander
R. B. Fitzgeorge
Affiliation:
PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire
A. Baskerville
Affiliation:
PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire
K. P. Lander
Affiliation:
Ministry of Agriculture, Central Veterinary Laboratories, New Haw, Weybridge, Surrey
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Young Rhesus monkeys (Macaca mulatta) were infected orally with a human strain of Campylobacter jejuni. The disease induced was mild, with inappetence and diarrhoea of short duration, but prolonged intermittent excretion of the bacteria in the faeces occurred. Bacteraemia was generally present for 2–3 days and later the organisms localized in the liver and gall bladder. Recovered animals, when challenged with the same strain, showed no clinical symptoms, no bacteraemia, and excreted the organisms in the faeces for only 3 days.

Type
Research Article
Information
Journal of Hygiene , Volume 86 , Issue 3 , June 1981 , pp. 343 - 351
Copyright
Copyright © Cambridge University Press 1981

References

REFERENCES

Anderson, W. A. D. (1966). Pathology, vol. 1, 5th ed, p. 221. St Louis: C. V. Mosby Co.Google Scholar
Angrist, A. & Mallov, M. (1948). Morphologic studies of the intestine in Salmonella infection in guinea pigs and mice. American Journal of Medical Science 251, 149–57.CrossRefGoogle Scholar
Blaser, M. J., Cravens, J., Powers, B. W., LaForce, F. M. & Wang, W. L. L. (1979). Campylobacter enteritis associated with unpasteurised milk. American Journal of Medicine 65, 715–18.CrossRefGoogle Scholar
Blaser, M. J.Hardesty, H. I., Powers, B. W. & Wang, W. L. L. (1980). Survival of Campylobacter fetus subsp. jejuni in Biological Milieu. Journal of Clinical Microbiology 11, 309–13.CrossRefGoogle Scholar
Butzler, J. P. (1979). Infection with Campylobacters. In Modern topics in infection. (ed. Williams, J. D.), pp. 214–39.Google Scholar
Butzler, J. P. & Skirrow, M. B. (1979). Campylobacter Enteritis. Clinics in Gastroenterology 8, 737–66.CrossRefGoogle ScholarPubMed
Cadranel, S., Rodesch, P., Butzler, J. P. & Dekeyser, P. (1973). Enteritis due to ‘related vibrio’ in children. American Journal of Diseases of Children 126, 152–5.Google ScholarPubMed
Darling, W. M., Peel, R. N., Skirrow, M. B. & Mulira, A. E. J. L. (1979). Campylobacter cholecystitis. Lancet i, 1302.CrossRefGoogle Scholar
Dekeyser, P., Gossuin-Detrain, M., Butzler, J. P. & Sternon, J. (1972). Acute enteritis due to related Vibrio: first positive stool culture. Journal of Infectious Diseases 125, 390–2.CrossRefGoogle Scholar
Grant, I. H., Richardson, N. J. & Bokkenheuser, V. D. (1980). Broiler chickens as potential source of Campylobacter infections in humans. Journal of Clinical Microbiology 11, 508–10.CrossRefGoogle ScholarPubMed
Itoh, T., Saito, K., Maruyama, T., Sakai, S., Ohashi, M. & Oka, A. (1980). An outbreak of acute enteritis due to C. fetus subsp. jejuni at a nursery school in Tokyo. Microbiology and Immunology 24, 371–9.CrossRefGoogle Scholar
King, E. O. (1957). Human infection with Vibrio fetus and a closely related Vibrio. Journal of Infectious Diseases 101, 119–28.CrossRefGoogle Scholar
Lander, K. P. & Gill, K. P. W. (1980). Experimental infection of the bovine udder with Campylobacter coli/jejuni. Journal of Hygiene 84, 421–8.CrossRefGoogle ScholarPubMed
Lawson, G. H. K. & Dow, C. (1965). The pathogenesis of oral Salmonella cholerae-suis infection in pigs. Journal of Comparative Pathology and Therapeutics. 75, 75–81.CrossRefGoogle Scholar
Robinson, D. A., Edgar, W. J., Gibson, G. L., Matchett, A. A. & Robertson, L. (1979). Campylobacter enteritis associated with the consumption of unpasteurised milk. British Medical Journal i, 1171–3.CrossRefGoogle Scholar
Skirrow, M. B. (1977). Campylobacter enteritis: a “new” disease. British Medical Journal 2, 9–11.CrossRefGoogle ScholarPubMed
Tribe, G. W. & Frank, A. (1980). Campylobacter in monkeys. Veterinary Record 106, 365–6.CrossRefGoogle ScholarPubMed
Veron, M. & Chatelain, R. (1973). Taxonomic Study of the genus Campylobacter Sebald and Veron, and Designation of the Neotype Strain for the Type Species. Campylobacter fetus (Smith and Taylor) Sebald and Veron International Journal of Systematic Bacteriology 23, 122–34.CrossRefGoogle Scholar
Wheeler, W. E. & Borchers, J. (1961). Vibrionic enteritis in infants. American Journal of Diseases of Children 101, 60–6.Google ScholarPubMed