Hostname: page-component-745bb68f8f-b6zl4 Total loading time: 0 Render date: 2025-01-08T07:17:56.023Z Has data issue: false hasContentIssue false
  • English
  • Français

Experimental infection of castrated lambs with Mycoplasma agalactiae

Published online by Cambridge University Press:  19 October 2009

K. J. MacOwan ,
T. F. Brand ,
N. McGillveray  and
A. R. Hunter
K. J. MacOwan
Affiliation:
Ministry of Agriculture, Fisheries and Food, Veterinary Laboratory, Eskgrove, Lasswade, Midlothian EH18 1HU
T. F. Brand
Affiliation:
Ministry of Agriculture, Fisheries and Food, Veterinary Laboratory, Eskgrove, Lasswade, Midlothian EH18 1HU
N. McGillveray
Affiliation:
Ministry of Agriculture, Fisheries and Food, Veterinary Laboratory, Eskgrove, Lasswade, Midlothian EH18 1HU
A. R. Hunter
Affiliation:
Ministry of Agriculture, Fisheries and Food, Veterinary Laboratory, Eskgrove, Lasswade, Midlothian EH18 1HU
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The course of experimental infection in groups of 6-month-old castrated lambs with field isolates of Mycoplasma agalactiae from France was followed culturally and serologically for 7 months. Infection with an ovine field isolate following inoculation by different routes and contact exposure was compared with that caused similarly by a caprine field isolate. The prolonged infections produced were symptomless apart from limited arthritis in one animal inoculated with the isolate from sheep and increased lachrymation in another associated with the goat isolate. The ovine isolate was more virulent in that ante- and post-mortem recoveries of the organism were more consistent and the serological responses more pronounced. Serological responses varied between animals and between strain infections, and the results of the film inhibition test were more consistent than those of the complement fixation test. The limitations of both these tests for detecting carrier infections are discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 93 , Issue 3 , December 1984 , pp. 455 - 463
Copyright
Copyright © Cambridge University Press 1984

References

Bridre, J. & Donatien, A. (1923). Le microbe de l'agalaxie contagieuse et sa culture in vitro. Comptes rendus hebdomadaire des séances de l'Académie des Sciences, Paris 177, 841–843.Google Scholar
Bridre, J. & Donatien, A. (1925). Le microbe de l'agalaxie contagieuse du mouton et de la chevre. Annales de l'Institut Pasteur 39, 925–951.Google Scholar
Cottew, G. S. (1979). Caprine-ovine mycoplasmas. In The Mycoplasmas. Volume 2. Human and Animal Mycoplasmas. (ed. Tully, J. G. and Whitcomb, R. F.), chapter 3, pp. 107–109. New York: Academic Press.Google Scholar
Etheridge, J. R., Foggie, A., Arisoy, F. & Erdag, O. (1969). Contagious agalactia of sheep and goats. A diagnostic complement fixation test. Pendik Veteriner Kontrol Ve Arastirma Enstitusu Dergisi 2, 101–119.Google Scholar
Foggie, A., Etheridge, J. R., Erdag, O. & Arisoy, F. (1970). Contagious agalactia of sheep and goats. The serial passage in goats of an attenuated strain of Mycoplasma agalactiae AIK40. Research in Veterinary Science 11, 477–479.CrossRefGoogle ScholarPubMed
Howard, C. J., Collins, J. & Gourlay, R. N. (1976). A radial growth precipitation test and its comparison with certain other serological tests for the detection of antibody in bovine sera to Mycoplasma agalactiae subsp. bovis. Veterinary Microbiology, 1, 23–30.CrossRefGoogle Scholar
MacOwan, K. J., Randall, C. J., Jones, H. G. R. & Brand, T. F. (1982). Association of Mycoplasma synoviae with respiratory disease of broilers. Avian Pathology 11, 235–244.CrossRefGoogle ScholarPubMed
Morgan, W. J. B., MacKinnon, D. J., Gill, K. P. W., Gower, S. G. M. & Noris, P. I. W. (1978). The complement fixation test. (CFT) In Brucellosis diagnosis, Standard Laboratory Techniques, 2nd ed, pp. 17–37. Ministry of Agriculture, Fisheries and Food (publications), Tolcarne Drive, Pinner, Middlesex HA5 2DT.Google Scholar
Morozzi, A., Diminioi, S. & Cardaras, P. (1973). A serological survey on contagious agalactia in sheep: the development of effective diagnostic methods. Atti della Società italiana delle scienze veterinaire 27, 628–633.Google Scholar
Perreau, P., Le Goff, C. & Giauffret, A. (1976). Le diagnostic serologique de l'agalaxie contagieuse des petits ruminants: un test de fixation du complement. Bulletin d'Académic Vétérinaire de France 49, 185–192.CrossRefGoogle Scholar
Ruhnke, H. L., Thawley, D. & Nelson, F. C. (1976). Bovine mastitis in Ontario due to Mycoplasma agalactiae subsp bovis. Canadian Journal of Comparative Medicine 40, 142–148.Google ScholarPubMed
Schaeren, W. & Nicolet, J. (1982). Application of a micro-Elisa to the serology of infectious agalactia of goats. Schweizer Archiv für Tierheilhunde, 124, 163–177.Google Scholar
Shabanov, M., Toshkov, A., Mikhailova, L. & Shirova, L. (1973). Experimental mastitis in ewes due to Mycoplasma agalactiae. Veterinarno Meditsinski Nauki Sofia 10, 81–84.Google Scholar
Thorns, C. J. & Boughton, E. (1978). Studies on film production and its specific inhibition with special reference to Mycoplasma bovis (M. agalactiae var. bovis). Zentralblatt für Veterinarmedizen B 25, 657–667.CrossRefGoogle ScholarPubMed
Toshkov, A., Mikhailova, L., Shirova, L. & Shabanov, M. (1974). Investigations of the infection and immune process in mycoplasmoses. 1. On some features accompanying experimental agalactia in sheep and goats. Izvestiya na Mikrobiologicheskiya Institut na Bulgarskata Akademiya na Naukite 25, 39–45.Google Scholar
Toshkov, A., Shirova, L., Mikhailova, L. & Shabanov, M. (1975). Investigations of the infection and immune process in mycoplasmoses. V. Experimental infection with Mycoplasma agalactiae in lambs. Acta Microbiologica Virologica el Immunologica 2, 42–47.Google Scholar
Toshkov, A., Shirova, L., Mikhailova, L. & Shabanov, M. (1976). Study of the infectious and immunisation processes in mycoplasmoses. VIII. Experimental chronic infection of sheep with Mycoplasma agalactiae during pregnancy, lambing and lactation. Acta microbiologica virologica et immunologica 4, 52–57.Google ScholarPubMed
Zavagli, V. (1951). L'agalaxie contagieuse des brebis et des chevres. Bulletin de l'office International des Epizoolies 35–36, 336–362.Google Scholar