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The epidemic cycle of Chlamydia pneumoniae infection in eastern Finland, 1972–1987

Published online by Cambridge University Press:  19 October 2009

M. Karvonen ,
J. Tuomilehto ,
J. Pitkäniemi  and
P. Saikku
M. Karvonen
Affiliation:
Department of Epidemiology, National Public Health Institute, Elimäenkatu 25, SF-00510 Helsinki, Finland Department of Bacteriology, National Public Health Institute, Helsinki, Finland
J. Tuomilehto
Affiliation:
Department of Epidemiology, National Public Health Institute, Elimäenkatu 25, SF-00510 Helsinki, Finland
J. Pitkäniemi
Affiliation:
Department of Epidemiology, National Public Health Institute, Elimäenkatu 25, SF-00510 Helsinki, Finland
P. Saikku
Affiliation:
Department of Virology, University of Helsinki, Helsinki, Finland
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The epidemic cycle of Chlamydia pneumoniae infection was examined in two areas in eastern Finland over a period of 15 years, 1972–87. The C. pneumoniae IgG antibody prevalence was determined with 5-year intervals in a random sample of the population aged 25–59 years. The total number of sera studied using immunofluorescence was 2387. In 1972 the antibody prevalence was 57% and it increased to 66% in 1977. Over the next 5 years the prevalence decreased to 44% in 1982, but by 1987 it had again increased to 59%. The temporal variation in prevalence was statistically significant (P < 0·001) and similar for both genders. Throughout the observation period the overall prevalence Mas 7–11% higher in men than in women (P < 0·01). The antibody prevalence increased with age, being the highest among the oldest study subjects of both genders. The periods of high and low prevalence alternated in an epidemic cycle (P < 0·001) of about 10 years

Type
Research Article
Information
Epidemiology & Infection , Volume 110 , Issue 2 , April 1993 , pp. 349 - 360
Copyright
Copyright © Cambridge University Press 1993

References

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