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The conglutination phenomenon: X. Conglutinin and immuno-conglutinin in guinea-pigs, pigs, donkeys, rats and mice

Published online by Cambridge University Press:  15 May 2009

Anne M. Coombs
Affiliation:
The Department of Pathology, University of Cambridge
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1. Immuno-conglutinin production by auto-stimulation was attempted in guinea-pigs, pigs, donkeys, rats and mice by the intravenous injection of a suspension of Gram-negative bacteria. The attempt was successful in rats and mice.

2. Experiments were carried out to elucidate the lack of response in guinea-pigs.

The author would like to thank Mr N. H. Hole of the Ministry of Agriculture Veterinary Laboratories at Weybridge, who inoculated and bled the donkeys used in these experiments.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1954

References

Blomfield, A. M., Coombs, R. R. A. & Hole, N. H. (1949). The conglutination phenomenon. V. Further experiments on the importance of the choice of complement when examining antisera for the presence of complement-fixing or complement-absorbing antibodies. J. Hyg., Camb., 47, 132.CrossRefGoogle ScholarPubMed
Blomfield, A. M., Herbertson, B. M. & Coombs, R. R. A. (1952). A simple device facilitating the intravenous injection of guinea-pigs. J. Path. Bact. 64, 894.CrossRefGoogle ScholarPubMed
Coombs, A. M. & Coombs, R. R. A. (1953). The conglutination phenomenon. IX. The production of immuno-conglutinin in rabbits. J. Hyg., Camb., 51, 509.Google ScholarPubMed
Streng, O. (1909). Ueber das Verkommen der Konglutinine in den Seren verschiedener Tiere, besonders der Weiderkäner. Z. ImmunForsch, 2, 415.Google Scholar
Streng, O. (1930). Immunokonglutinin—Antikomplement. Acta. path. microbiol. scand. 2, 411.Google Scholar
Wartiovaara, T. W. (1932). Über die Entwicklung der konglutinierenden Eigenschaft bei der Immunsierung. Acta Soc. Med. ‘Duodecim’, Ser. A, 14, Fasc. 3.Google Scholar