Hostname: page-component-7bb8b95d7b-5mhkq Total loading time: 0 Render date: 2024-09-15T01:03:43.928Z Has data issue: false hasContentIssue false
  • English
  • Français

The concurrent prevalence of chloramphenicol-sensitive and multidrug-resistant Salmonella typhi in Vellore, S. India

Published online by Cambridge University Press:  15 May 2009

M. V. Jesudason ,
R. John  and
T. J. John
M. V. Jesudason
Affiliation:
Department of Microbiology, Christian Medical College & Hospital, Vellore 632 004, India
R. John
Affiliation:
Department of Microbiology, Christian Medical College & Hospital, Vellore 632 004, India
T. J. John
Affiliation:
Department of Microbiology, Christian Medical College & Hospital, Vellore 632 004, India
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A multidrug resistant (MDR) variety of Salmonella typhi emerged as the cause of epidemic typhoid fever in some Asian countries including India, during the late 1980s. We faced the epidemic from April 1990 to the first quarter of 1993. However, during this period we continued to isolate chloramphenicol sensitive (CS) S. typhi also. The relative prevalences showed that the frequency of CS variety was unaffected by the epidemic of MDR variety. This is an unusual epidemiological pattern, which indicates that there may have been factors which favoured the epidemic of the MDR variety but not the CS one.

Type
Research Article
Information
Epidemiology & Infection , Volume 116 , Issue 2 , April 1996 , pp. 225 - 227
Copyright
Copyright © Cambridge University Press 1996

References

1.Goldstein, FW, Chumpitaz, JC, Guerara, JM, Papadopoulou, B, Acar, JF, Vieu, JF. Plasmid mediated resistance to multiple antibiotics in S. typhi. J Infect Dis 1986; 153: 261–6.CrossRefGoogle Scholar
2.Wang, F, Gu, XJ, Zhang, MF, Tai, TY. Treatment of typhoid fever with ofloxacin. J Antimicrob Chemother 1989; 23: 785–8.CrossRefGoogle ScholarPubMed
3.Jesudason, MV, John, TJ. Multi resistant S. typhi in India. Lancet 1990; 336: 252.CrossRefGoogle Scholar
4.Threfall, EJ, Ward, LR, Rowe, B, Raghupathi, S, Chandrasekaran, V, Vandepitte, J, Lemmens, P. Wide spread occurrence of multidrug resistant S. typhi in India. Eur J Clin Microbiol Infect Dis 1992; 11: 990–3.CrossRefGoogle Scholar
5.Jesudason, MV, John, TJ. Plasmid mediated multidrug resistance in S. typhi Ind J Med Res 1992; 95: 66–7.Google Scholar
6.Koshi, G, Alex, W, Menon, T. An improved technique for blood culture. Indian J Med Res 1981; 73: 733–8.Google ScholarPubMed
7.Bhat, P, Myers, RM. Standard methods and procedures used in the bacteriology laboratory of the Vellore Christian Medical College Hospital for isolation and identification of organisms belonging to the family Chloramphenicol sensitive and multidrug resistant S. typhi Enterobacteriaceae. Indian J Med Res 1962; 50: 559–66.Google Scholar
8.Bauer, AW, Kirby, WM, Sherris, JC, Turck, M. Antibiotic susceptibility testing by a standardised simple disc method. Am J Clin Pathol 1966; 45: 493–8.CrossRefGoogle Scholar
9.Jesudason, MV, John, TJ. The appearance and spread of V. cholerae 0139 in India. Indian J Med Res 1994; 99: 97–100.Google ScholarPubMed
10.World Health Organisation. Epidemic diarrhoea due to V. cholerae non 01. Weekly Epidemiol Rec 1993; 68: 141–7.Google Scholar
11.Ramanan, A, Pandit, N, Yeshwanth, M. Unusual complications in a multidrug resistant S. typhi outbreak. Indian Paediatr 1992; 29: 118–20.Google Scholar
12.Sharma, A, Gathwala, G. Clinical profile and outcome in enteric fever. Indian Paediatr 1993; 30: 47–50.Google ScholarPubMed