Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-05T19:44:54.761Z Has data issue: false hasContentIssue false
  • English
  • Français

The Complement Fixation Test in Relation to the Gonococcus and Allied Organisms

Published online by Cambridge University Press:  15 May 2009

John O. Oliver
John O. Oliver
Affiliation:
(Assistant Pathologist, St Thomas's Hospital, late Assistant Pathologist, Venereal Diseases Department.)
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The work described in this paper was commenced in 1926 in order to demonstrate whether or no infections with the M. catarrhalis afford positive reactions with gonococcal antigens. It had already been shown that an antigen of M. catarrhalis might react with the sera from gonococcal infections. Later it was decided to investigate aberrant forms of M. catarrhalis and allied organisms and also to test whether sera which react very strongly to the Wassermann reaction might also react non-specifically to the Gonococcal Complement Fixation test, possibly to such a degree as to detract from the value of the latter. Such a non-specific reaction might be of the nature of a group fixation (the Wassermann being not anti-spirochactal but probably anti-lipoidal), or to adventitious substances introduced in the preparation of the gonococcal extracts from cultures derived from patients with secondary syphilis.

Type
Research Article
Information
Journal of Hygiene , Volume 29 , Issue 3 , December 1929 , pp. 259 - 272
Copyright
Copyright © Cambridge University Press 1929

References

REFERENCES

Schwartz, H. J. and McNeil, A. (1911). Am. J. Med. Sc. N.S. 141, 693.CrossRefGoogle Scholar
Schwartz, H. J. (1912). Am. J. Med. Sc. N.S. 144, 369.Google Scholar
Thomas, B. A., Ivy, R. H. and Birdsall, J. C. (1915). Arch. Int. Med. 15, 265.Google Scholar
Uhle, A. A. and Mackinney, W. H. (1915). N. York M. J. 102, 737.Google Scholar
Torrey, J. C. and Bucknell, G. T. (1922). J. Immunol. 7, 305.CrossRefGoogle Scholar
The Medical Research Council (1923). Special report series, No. 19.Google Scholar
Wilson, S. P. (1928). J. Path. and Bact. 31, 477.Google Scholar